Protein Alignment colt and SLC25A47

DIOPT Version :10

• Sequence 1: NP_477221.1
• Gene: colt / 33470
• FlyBaseID: FBgn0019830
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_997000.2
• Gene: SLC25A47 / 283600
• HGNCID: 20115
• Length: 308
• Species: Homo sapiens
• Alignment Length: 621
• Identity: 112/621 - (18%)
• Similarity: 200/621 - (32%)
• Gaps: 200/621 - (32%)

  Fly    59 WRTVAQRSLQHQAAHPRSERKAKNVVYFIGD--GMGLSTVA-----------AARMYLGNENMYL 110
            |:  .:.:|..:..||.....|...|  :||  |..|:.||           |..::.|...:.:
Human   447 WQ--CEATLHGEQGHPWGRFGAALTV--LGDVNGDDLADVAIGAPGEEESRGAVYIFHGASRLEI 507

  Fly   111 S------------FEKFPYFGLAKT---YCVNRQVADSACTATAYLSGVKINYGMLNVAASVKRS 160
            |            |.:..|||.:.:   ......:.|.|..:..:|..::.. .:|.::::::.:
Human   508 SPSPSQRISASRIFPRLQYFGQSLSGGQDLTGDGLVDLAVGSKGHLLLLRTR-PILRMSSTIQFT 571

  Fly   161 SCEYDRNATEFKGLLEWAQQAGKATGIVTTTRITHATPGGTYASSADRDW--------------E 211
            ..|..|:..|.:|.:...|..|.|| :...|..:..|..|...|....|.              |
Human   572 PTEISRSVFECQGQVTREQTLGTAT-VCLRTYESSKTQRGDLQSIVTFDLALDPGRLSPRAIFKE 635

  Fly   212 DDTE---------VNNDC-PTTR-----QEDKPVDIATQLVYGSVG------KNLKVALGCGRRH 255
            ..|:         :::.| |.|.     .||....|..:|.:..||      :||:..|....:.
Human   636 TKTQALTKVRTLGLSSHCEPVTLLLPACVEDSVTPITLRLNFSLVGVPIPSLQNLQPMLAVDEQT 700

  Fly   256 FIPADVKDEDGKAGKRSDGVNLIEAWKEVHADMGEARYVSDKKSLLEAAKSKKLDYLLGLFDSSH 320
            :..|.:..|      ::.|.:.|     ...|:|......|.|:|:..:
Human   701 YFTASLPFE------KNCGADHI-----CQDDLGIIFGFPDLKTLVVGS---------------- 738

  Fly   321 CLYNLEIDDQKLGDVKPKLTDMVDAALSMLEDSEQGY----VLFVEGGLIDTAHHSNRPRLSLEE 381
               |||:                ..|:::..|.|..|    .||...||........:..|..|:
Human   739 ---NLEL----------------SVAVTVTNDGEDSYGTTITLFYPVGLSFRRVAEAQVFLRTED 784

  Fly   382 TKEFHK----AIELARTRTSEEDTLIVVSSDHSHTLMYNG--------------YPTRGNDILGI 428
            |:::.:    ::.|....|.:....|..:|..|..:::.|              ....|:.:|..
Human   785 TQQWQQQGRHSLHLMCDSTPDRSQGIWSTSCSSRHVIFRGGSQMTFLVTFDVSPKAELGDRLLLR 849

  Fly   429 GDISDKDGLP-----------------YTTLSYANGEGFYQTYADGNPSKRLDVTGYDF--SDYR 474
            ..:|.::|:|                 ||.:|..:....|..::....| |:.|..:.|  ::..
Human   850 ARVSSENGVPETRKTTFQLELPVKYAVYTVISSHDQFTKYLNFSASEKS-RVSVVEHRFQVNNLG 913

  Fly   475 QRYLAT-----VPLSSETHGGEDVGV----YASGPGAHLFGGS---------TEQNVIPLLIAYA 521
            ||.|..     ||...:   ||.|..    :...|....:...         |.....|:|....
Human   914 QRDLPVSINFRVPTELK---GETVWTVMVSHPQNPSTQCYQNRLKPTQFDLLTHMQKSPVLDCSI 975

  Fly   522 AN------------IGDE----------FGWVTSTV 535
            |:            |.||          |||::.|:
Human   976 ADCLHFRCDIPSLGIQDELDFILKGNLSFGWISQTL 1011

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
colt	NP_477221.1	Mito_carr	12..107	CDD:395101	14/60 (23%)
		Mito_carr	112..202	CDD:395101	19/92 (21%)
		Mito_carr	210..299	CDD:395101	21/123 (17%)
SLC25A47	NP_997000.2	Solcar 1	1..80
		Mito_carr	2..77	CDD:395101
		Solcar 2	93..206
		Mito_carr	100..208	CDD:395101
		Solcar 3	215..302
		Mito_carr	221..302	CDD:395101