Protein Alignment aph-1 and zgc:114200

DIOPT Version :9

• Sequence 1: NP_001259963.1
• Gene: aph-1 / 33467
• FlyBaseID: FBgn0031458
• Length: 238
• Species: Drosophila melanogaster
• Sequence 2: NP_001025300.1
• Gene: zgc:114200 / 559336
• ZFINID: ZDB-GENE-050913-96
• Length: 253
• Species: Danio rerio
• Alignment Length: 246
• Identity: 114/246 - (46%)
• Similarity: 162/246 - (65%)
• Gaps: 12/246 - (4%)

  Fly     1 MTLPEFFGCTFIAFGPPFALFVFTIANDPVRIIILIAAAFFWLLSLLISSL-WYALIPL------ 58
            |||..||||.||||||.|||||||:|.||:|:|||||.|||||||||:||| |:..:..
Zfish     1 MTLAVFFGCAFIAFGPAFALFVFTVAKDPLRVIILIAGAFFWLLSLLLSSLVWFIAVKASNSQDP 65

  Fly    59 ---KEFLAFGVVFSVCFQEAFRYIIYRILRSTEQGLHAVAEDTRVTDNKHILAYVSGLGFGIISG 120
               :..|.|||.|||..||.||:..||:||...:||.|:::|.....:...:|||:|||||::.|
Zfish    66 SLPRGLLIFGVFFSVLLQEVFRFAYYRLLRKATEGLAAISDDASSAISVRQMAYVAGLGFGVMRG 130

  Fly   121 MFALVNVLADMSGPGTMGLKGGTELFFVTSAAQALSIILLHTFWSVIFFNAFDTNNYIHIGYVVF 185
            .|:::|:|:|..||||:|:.|.::.:|:|:|...|::.||||||.|:||...:.:::..|..||.
Zfish   131 AFSMINILSDSLGPGTVGIFGDSQYYFITAALMTLALTLLHTFWGVLFFEGCEKSSWWVIAVVVS 195

  Fly   186 SHLFVSLITLLNANELYTTTLLINYLVTILTGVLAFRVAGGTSRSFRKFIT 236
            .||.|:.::||  |.||..:|...|.:|:|.|:.||..:||:.::.....|
Zfish   196 LHLLVAGLSLL--NPLYEGSLPPVYCITLLMGIWAFFSSGGSLQNLSALCT 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aph-1	NP_001259963.1	Aph-1	2..225	CDD:283708	110/232 (47%)
zgc:114200	NP_001025300.1	Aph-1	2..233	CDD:283708	110/232 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581640
Domainoid	1	1.000	220	1.000	Domainoid score	I2561
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	227	1.000	Inparanoid score	I3457
OMA	1	1.010	-	-		QHG55474
OrthoDB	1	1.010	-	-		D1085102at2759
OrthoFinder	1	1.000	-	-		FOG0003244
OrthoInspector	1	1.000	-	-		otm25633
orthoMCL	1	0.900	-	-		OOG6_104863
Panther	1	1.100	-	-	LDO	PTHR12889
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3174
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.910