DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx21 and SNX29

DIOPT Version :9

Sequence 1:	NP_608709.1	Gene:	Snx21 / 33466	FlyBaseID:	FBgn0031457	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	XP_011521040.1	Gene:	SNX29 / 92017	HGNCID:	30542	Length:	879	Species:	Homo sapiens

Alignment Length:	238	Identity:	56/238 - (23%)
Similarity:	94/238 - (39%)	Gaps:	77/238 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 FVVYE--LTVKQDGATEDTQPAKIERRYTDFRELYLGLKRQHPAEMANKYFPAKVLMGNFKSELI 155
            |.||:  :.:|.|       ...|.||||:||.|:..|:.::|...|..:.|.|.         |
Human   685 FHVYQVYIRIKDD-------EWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKA---------I 733

  Fly   156 GERSAAFEAFLTYVAS-QAMLRDSEYFLRFLQHDELTRA--CQFLDERRNEMAIPILENCFR-LL 216
            |.:.....|::|..|| .|.|..:...|......|:|.:  .:|::|||.:     |:|..| ::
Human   734 GNKPPPSPAWMTAAASLLASLLPALPPLNLQVTSEVTSSQDAKFVEERRKQ-----LQNYLRSVM 793

  Fly   217 NKIYMNRSRPVLLILCRLVAACTSSPVPHHAAERWALLALSRFETLCDIDLLPLYIP-------- 273
            ||:.                    ..||..||.       .:.|||  |.|:|.::.
Human   794 NKVI--------------------QMVPEFAAS-------PKKETL--IQLMPFFVTSWCWDPEN 829

  Fly   274 LLHTC---------AHLWWQRG--QDQKPITDRLTDMSKQGIN 305
            ...||         :|.|...|  :..:||:::  ::..:|::
Human   830 QTQTCLQGTLGYCQSHFWISCGWWKSWRPISNQ--EVGGKGLD 870

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx21	NP_608709.1	PX_SNX20_21_like	71..188	CDD:132812	27/97 (28%)
SNX29	XP_011521040.1	RUN	54..189	CDD:280855
		Ax_dynein_light	<487..552	CDD:287215
		PX_RUN	668..820	CDD:132810	48/184 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810