Protein Alignment Snx21 and SNX21

DIOPT Version :10

• Sequence 1: NP_608709.1
• Gene: Snx21 / 33466
• FlyBaseID: FBgn0031457
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: NP_219489.1
• Gene: SNX21 / 90203
• HGNCID: 16154
• Length: 373
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 94/317 - (29%)
• Similarity: 135/317 - (42%)
• Gaps: 39/317 - (12%)

  Fly    18 DGDPPGPDEL---DSPAIEAAALDIPPPESDKALQ------KGVWERATSAEYKPTTDGSTVLRF 73
            |.:..|||:|   |..:.|.|... |||:.....|      :..|:::.:      |.....|.|
Human    76 DDEEAGPDQLPLGDGTSGEDAERS-PPPDGQWGSQLLARQLQDFWKKSRN------TLAPQRLLF 133

  Fly    74 DILLAHIM--PPDGEDVKIKRFVVYELTVKQDGATEDTQPAKIERRYTDFRELYLGLKRQHPAEM 136
            ::..|:::  ||       .::|:|.|.|...| ..|.|||:|.|||:||..|:..|:||....|
Human   134 EVTSANVVKDPP-------SKYVLYTLAVIGPG-PPDCQPAQISRRYSDFERLHRNLQRQFRGPM 190

  Fly   137 ANKYFPAKVLMGNFKSELIGERSAAFEAFLTYVASQAMLRDSEYFLRFLQHDELTRACQFLDERR 201
            |...||.|.|..||.:|.|..||.|||.||.::.:...||.:.....|....||.||........
Human   191 AAISFPRKRLRRNFTAETIARRSRAFEQFLGHLQAVPELRHAPDLQDFFVLPELRRAQSLTCTGL 255

  Fly   202 NEMAIPILENCFRLLNKI--YMNRSRPVLLILCRLVAAC---TSSPVPHHAAERWALLALSRFET 261
            ...|:.:..|.::|..::  .....|| ||.|..| |.|   ...|....|....||      :.
Human   256 YREALALWANAWQLQAQLGTPSGPDRP-LLTLAGL-AVCHQELEDPGEARACCEKAL------QL 312

  Fly   262 LCDIDLLPLYIPLLHTCAHLWWQRGQDQKPITDRLTDMSKQGINTANTESLMQAIHK 318
            |.|..|.||..|.|.....|.|:.|.|::....||..:.:.|:......||.:.:.|
Human   313 LGDKSLHPLLAPFLEAHVRLSWRLGLDKRQSEARLQALQEAGLTPTPPPSLKELLIK 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snx21	NP_608709.1	PX_SNX20_21_like	71..188	CDD:132812	44/118 (37%)
SNX21	NP_219489.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..107		11/31 (35%)
		PX_SNX21	131..242	CDD:132834	44/118 (37%)
		Spy	164..>353	CDD:443119	65/196 (33%)
		TPR repeat	244..268	CDD:276809	5/23 (22%)
		TPR repeat	281..312	CDD:276809	12/38 (32%)
		TPR repeat	326..353	CDD:276809	7/26 (27%)