DRSC/TRiP Functional Genomics Resources

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Protein Alignment Snx21 and SNX21

DIOPT Version :9

Sequence 1:NP_608709.1 Gene:Snx21 / 33466 FlyBaseID:FBgn0031457 Length:326 Species:Drosophila melanogaster
Sequence 2:NP_219489.1 Gene:SNX21 / 90203 HGNCID:16154 Length:373 Species:Homo sapiens


Alignment Length:317 Identity:94/317 - (29%)
Similarity:135/317 - (42%) Gaps:39/317 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 DGDPPGPDEL---DSPAIEAAALDIPPPESDKALQ------KGVWERATSAEYKPTTDGSTVLRF 73
            |.:..|||:|   |..:.|.|... |||:.....|      :..|:::.:      |.....|.|
Human    76 DDEEAGPDQLPLGDGTSGEDAERS-PPPDGQWGSQLLARQLQDFWKKSRN------TLAPQRLLF 133

  Fly    74 DILLAHIM--PPDGEDVKIKRFVVYELTVKQDGATEDTQPAKIERRYTDFRELYLGLKRQHPAEM 136
            ::..|:::  ||       .::|:|.|.|...| ..|.|||:|.|||:||..|:..|:||....|
Human   134 EVTSANVVKDPP-------SKYVLYTLAVIGPG-PPDCQPAQISRRYSDFERLHRNLQRQFRGPM 190

  Fly   137 ANKYFPAKVLMGNFKSELIGERSAAFEAFLTYVASQAMLRDSEYFLRFLQHDELTRACQFLDERR 201
            |...||.|.|..||.:|.|..||.|||.||.::.:...||.:.....|....||.||........
Human   191 AAISFPRKRLRRNFTAETIARRSRAFEQFLGHLQAVPELRHAPDLQDFFVLPELRRAQSLTCTGL 255

  Fly   202 NEMAIPILENCFRLLNKI--YMNRSRPVLLILCRLVAAC---TSSPVPHHAAERWALLALSRFET 261
            ...|:.:..|.::|..::  .....|| ||.|..| |.|   ...|....|....||      :.
Human   256 YREALALWANAWQLQAQLGTPSGPDRP-LLTLAGL-AVCHQELEDPGEARACCEKAL------QL 312

  Fly   262 LCDIDLLPLYIPLLHTCAHLWWQRGQDQKPITDRLTDMSKQGINTANTESLMQAIHK 318
            |.|..|.||..|.|.....|.|:.|.|::....||..:.:.|:......||.:.:.|
Human   313 LGDKSLHPLLAPFLEAHVRLSWRLGLDKRQSEARLQALQEAGLTPTPPPSLKELLIK 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Snx21NP_608709.1 PX_SNX20_21_like 71..188 CDD:132812 44/118 (37%)
SNX21NP_219489.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..107 11/31 (35%)
PX_SNX21 131..242 CDD:132834 44/118 (37%)
TPR repeat 244..268 CDD:276809 5/23 (22%)
TPR_12 247..312 CDD:290160 16/72 (22%)
TPR repeat 281..312 CDD:276809 12/38 (32%)
TPR repeat 326..353 CDD:276809 7/26 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165159820
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2101
Hieranoid 00.000 Not matched by this tool.
Homologene 1 1.000 - - H43132
Inparanoid 1 1.050 87 1.000 Inparanoid score I5147
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1322681at2759
OrthoFinder 1 1.000 - - FOG0004256
OrthoInspector 1 1.000 - - otm40579
orthoMCL 1 0.900 - - OOG6_109685
Panther 1 1.100 - - LDO PTHR20939
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5585
SonicParanoid 1 1.000 - - X6082
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1312.790

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