DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx21 and SNX14

DIOPT Version :9

Sequence 1:	NP_608709.1	Gene:	Snx21 / 33466	FlyBaseID:	FBgn0031457	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001337461.1	Gene:	SNX14 / 57231	HGNCID:	14977	Length:	967	Species:	Homo sapiens

Alignment Length:	186	Identity:	37/186 - (19%)
Similarity:	61/186 - (32%)	Gaps:	52/186 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 PPDGEDVKIKRFVVYELTVKQD---GATEDTQPAKIERRYTDFRELYLGLKRQHPAEMANKYFPA 143
            |......|.:|..|:.:.|:::   ....:.:...:.|||.:|..|...|...|.| ..:...|:
Human   599 PSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGA-FPDAQLPS 662

  Fly   144 KVLMGNFKSELIGERSAAFEAFLTYVASQAMLRDSEYFLRFLQHDELTRA-------------CQ 195
            |.::|....|.:..:...|:               ||..:.|||.||:.:             .|
Human   663 KRIIGPKNYEFLKSKREEFQ---------------EYLQKLLQHPELSNSQLLADFLSPNGGETQ 712

  Fly   196 FLD--------------------ERRNEMAIPILENCFRLLNKIYMNRSRPVLLIL 231
            |||                    :.:.:...|.:.|............|||.|.||
Human   713 FLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSRPELTIL 768

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx21	NP_608709.1	PX_SNX20_21_like	71..188	CDD:132812	22/108 (20%)
SNX14	NP_001337461.1	PXA	151..320	CDD:308031
		RGS_SNX14	361..487	CDD:188677
		PX_SNX14	585..707	CDD:132787	25/123 (20%)
		Nexin_C	828..932	CDD:312222
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900