DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx21 and snx13

DIOPT Version :9

Sequence 1:	NP_608709.1	Gene:	Snx21 / 33466	FlyBaseID:	FBgn0031457	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	XP_021323912.1	Gene:	snx13 / 503733	ZFINID:	ZDB-GENE-050306-12	Length:	966	Species:	Danio rerio

Alignment Length:	247	Identity:	57/247 - (23%)
Similarity:	87/247 - (35%)	Gaps:	64/247 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IHAVMAKRLHHQPTFDGDPPGPDELDSPAIEAAALDIPPPESDKALQKGVWERATSAEYKPTTDG 67
            ::.:|.|..|:.|:|...|.....|       |.||:....|.:....|..|   |....||  |
Zfish   491 VYDMMLKHEHYYPSFRQHPLYVRML-------AELDMLKEPSYRGSDDGDGE---SFNGSPT--G 543

  Fly    68 STVLRFDILLA---------HIMPPDGEDVKI-------------KRFVVYELTV--KQDGATED 108
            |..|..|.|.:         |....|..|..:             |.:.:|.:||  |....:||
Zfish   544 SINLSLDDLSSGSVDESVQLHAFISDTADAFLNPLPVAGVCNDHGKTYALYTITVIRKNSDGSED 608

  Fly   109 TQPAKIERRYTDFRELYLGLKRQHPAEMANKYFPAKVLMGNFKSELIGERSAAFEAFLTYVASQA 173
            |.  |..|||:||.:.::.:..|..:.......|.|....|...|.:.:|.
Zfish   609 TW--KTYRRYSDFHDFHMRITEQFESLAPILKLPGKKTFNNMDREFLEKRK-------------- 657

  Fly   174 MLRDSEYFLRFLQHDELTRACQFLDERRNEMAIPILENCFRLLNKIYMNRSR 225
              :|...:|:.|.:.|:.:||..|        :|.:.:.  |.||.|....|
Zfish   658 --KDLNAYLQLLLNPEMVKACPIL--------MPYVYDF--LENKAYSKGKR 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx21	NP_608709.1	PX_SNX20_21_like	71..188	CDD:132812	29/140 (21%)
snx13	XP_021323912.1	PXA	98..284	CDD:321992
		RGS	378..513	CDD:321993	6/21 (29%)
		PX_SNX13	559..690	CDD:132783	32/158 (20%)
		Nexin_C	806..915	CDD:312222
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900