DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snx21 and snz

DIOPT Version :9

Sequence 1:	NP_608709.1	Gene:	Snx21 / 33466	FlyBaseID:	FBgn0031457	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001284993.1	Gene:	snz / 31704	FlyBaseID:	FBgn0029976	Length:	1117	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	58/273 - (21%)
Similarity:	98/273 - (35%)	Gaps:	98/273 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PDELDSPAIE------AAALDIPPPESDKALQKGVWERATSAE-YKPTTDGS------TVLRFDI 75
            ||.::...::      |||          |:.|..:|.|.|.| :....:.|      :::|..|
  Fly   291 PDYINQKVVQNIETRLAAA----------AMSKRSYEYAASFEDFLKIINNSGNLEELSLIRKSI 345

  Fly    76 L--LAHI-----------MPPDGED-----------VKIKRFVVYELTVKQDGATE--------- 107
            :  |.|.           :.||.||           |::||: |.:||:.: |..|
  Fly   346 VNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAAVRLKRY-VRQLTMAK-GECEKNLAKFGWN 408

  Fly   108 -----DTQPAKIE-------RRY-TDFRE---------LYLG---LKRQHPA---EMANKYFPAK 144
                 |.....:|       ||| |.|.|         .||.   :|..|.:   ::..:.|...
  Fly   409 GNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAVEEIKHAHKSASHQLGTEIFYTY 473

  Fly   145 VLMGNFKSELIGERSAAFEAFLT--------YVASQAMLR--DSEYFLRFLQHDELTRACQFLDE 199
            :.:...:.::........|.||.        |...:.:||  :.:|:..|:..|:..:..:.||.
  Fly   474 IRVPKSEIQIDKHERKLIETFLLGDAEPDIFYDIQRNVLRTLEEKYYPPFVLSDQYRQLKEALDS 538

  Fly   200 RRNEMAIPILENC 212
              ||:|.|.|..|
  Fly   539 --NEIADPTLLMC 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx21	NP_608709.1	PX_SNX20_21_like	71..188	CDD:132812	37/187 (20%)
snz	NP_001284993.1	PXA	142..299	CDD:280373	2/7 (29%)
		RGS_SNX25	422..531	CDD:188675	20/108 (19%)
		PX_SNX25	645..788	CDD:132788
		Nexin_C	882..987	CDD:285792
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900