DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx21 and RPS6KC1

DIOPT Version :9

Sequence 1:	NP_608709.1	Gene:	Snx21 / 33466	FlyBaseID:	FBgn0031457	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_036556.2	Gene:	RPS6KC1 / 26750	HGNCID:	10439	Length:	1066	Species:	Homo sapiens

Alignment Length:	128	Identity:	32/128 - (25%)
Similarity:	58/128 - (45%)	Gaps:	8/128 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 FVVYELT--VKQDGATEDTQPAKIERRYTDFRELYLGLKRQHPAEMA-NKYFP--AK-VLMGNFK 151
            :.||::|  |......||.|...:.:||:||::|:..|.:.|..... ::.||  || ::.|.|.
Human    27 YTVYKVTARVVSRRNPEDVQEIIVWKRYSDFKKLHKELWQIHKNLFRHSELFPPFAKGIVFGRFD 91

  Fly   152 SELIGERSAAFEAFLTYVASQAMLRDSEYFLRFLQHDELTRACQFLD--ERRNEMAIPILENC 212
            ..:|.||....|..|.:.|:...|.:|:....|.:...:..:.:.:.  |..::..|.....|
Human    92 ETVIEERRQCAEDLLQFSANIPALYNSKQLEDFFKGGIINDSSELIGPAEAHSDSLIDTFPEC 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx21	NP_608709.1	PX_SNX20_21_like	71..188	CDD:132812	29/100 (29%)
RPS6KC1	NP_036556.2	PX_RPK118_like	11..128	CDD:132820	29/100 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	207..228
		MIT_SNX15	238..312	CDD:239140
		PKc_like	335..>421	CDD:304357
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	441..509
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	553..596
		S_TKc	<875..1056	CDD:214567
		STKc_RPK118_like	<879..1056	CDD:270728
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900