DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx21 and Snx13

DIOPT Version :9

Sequence 1:	NP_608709.1	Gene:	Snx21 / 33466	FlyBaseID:	FBgn0031457	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	XP_006515125.3	Gene:	Snx13 / 217463	MGIID:	2661416	Length:	1144	Species:	Mus musculus

Alignment Length:	203	Identity:	43/203 - (21%)
Similarity:	80/203 - (39%)	Gaps:	39/203 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 TFDGDPPGPDELDSPAIEAAALDIPPPESDKALQKGVWERAT-SAEYKPTTDGSTVLRFDILLAH 79
            :|:|.|.|       :|..:..|:....||.::|...:...| .|:|.|           ..:|.
Mouse   710 SFNGSPTG-------SINLSLDDLSSVTSDDSVQLHAYISDTVYADYDP-----------YAVAG 756

  Fly    80 IMPPDGEDVKIKRFVVYELTV-KQDGATEDTQPAKIERRYTDFRELYLGLKRQHPAEMANKYFPA 143
            :....|     |.:.:|.:|| :::..||:..  |..|||:||.:.::.:..|.....:....|.
Mouse   757 VCNDHG-----KTYALYAITVHRRNLNTEEMW--KTYRRYSDFHDFHMRITEQFENLSSILKLPG 814

  Fly   144 KVLMGNFKSELIGERSAAFEAFLTYVASQAMLRDSEYFLR----FLQH--------DELTRACQF 196
            |....|...:.:.:|.....|:|..:.:..|::.|.....    ||::        |...:...|
Mouse   815 KKTFNNMDRDFLEKRKKDLNAYLQLLLTPEMMKASPALAHCVYDFLENKAYSKGKGDFARKMDTF 879

  Fly   197 LDERRNEM 204
            ::..||.|
Mouse   880 VNPLRNSM 887

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx21	NP_608709.1	PX_SNX20_21_like	71..188	CDD:132812	25/129 (19%)
Snx13	XP_006515125.3	PHA03381	6..>146	CDD:177618
		PXA	273..460	CDD:214611
		RGS_SNX13	553..687	CDD:188674
		PX_SNX13	733..863	CDD:132783	30/147 (20%)
		Nexin_C	979..1087	CDD:370015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900