DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx21 and Snx25

DIOPT Version :9

Sequence 1:	NP_608709.1	Gene:	Snx21 / 33466	FlyBaseID:	FBgn0031457	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001359271.1	Gene:	Snx25 / 102141	MGIID:	2142610	Length:	986	Species:	Mus musculus

Alignment Length:	251	Identity:	47/251 - (18%)
Similarity:	86/251 - (34%)	Gaps:	76/251 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 EAAALDIPPPESDKALQK-GVWERATSAEYKPTTDGSTVLRFDILLAHIMPPDGEDVKIKRFVVY 96
            |..||.:....:|...:. |:|                  |..|..|.:...:||.:.. .||
Mouse   635 ECTALQLHMARTDWWCENLGLW------------------RASITSAEVTEENGEQMPC-YFV-- 678

  Fly    97 ELTVKQDGATEDTQPAKIERRYTDFRELYLGLKRQHPAEMANKYFP--AKVLMGNFKSELIGERS 159
            .:.:::.|..| |:...:.||.::|:.|:..|....|: :.....|  :|:...:...:.:|:..
Mouse   679 RVNLQEVGGVE-TKNWTVPRRLSEFQNLHRKLSECVPS-LKKVQLPSLSKLPFKSIDHKFLGKSR 741

  Fly   160 AAFEAFLTYVASQAMLRDSEYFLRFL-----------------------------------QHDE 189
            ....|||..:.|...|..||....||                                   |.:|
Mouse   742 NQLNAFLQNLLSDERLFQSEALYAFLSPSPDYLKVIDVQGKKTSFSLSSFLEKLPRDFFSHQEEE 806

  Fly   190 LTRACQF------LDERRNEMAIPILENCFRLLNKIYMNRS-----RPVLLILCRL 234
            :......      :|.:::.:|.|    ||.|:.:|:..|.     |..|:.|.::
Mouse   807 IEEDSDLSDYGDDVDGKKDSLAEP----CFMLIGEIFELRGMFKWVRRTLIALVQV 858

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx21	NP_608709.1	PX_SNX20_21_like	71..188	CDD:132812	29/153 (19%)
Snx25	NP_001359271.1	PXA	148..303	CDD:366970
		RGS	437..545	CDD:383028
		End3	<558..645	CDD:372297	3/9 (33%)
		PX_SNX25	648..770	CDD:132788	30/144 (21%)
		Nexin_C	847..950	CDD:370015	3/12 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900