Protein Alignment Tnpo-SR and xpo1

DIOPT Version :9

• Sequence 1: NP_001259961.1
• Gene: Tnpo-SR / 33465
• FlyBaseID: FBgn0031456
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_002939551.2
• Gene: xpo1 / 100380168
• XenbaseID: XB-GENE-993240
• Length: 1071
• Species: Xenopus tropicalis
• Alignment Length: 1008
• Identity: 178/1008 - (17%)
• Similarity: 366/1008 - (36%)
• Gaps: 263/1008 - (26%)

  Fly     6 VDVVYQAISALFQGNNPKEQEKANKWLQDFQKSIYSWTIADELLHQKRDLHANYFAAQTMRNKIQ 70
            ::::...::.|:.|.. .:|..|.:.|...::...:||..|.:|...::::..|:..|.:.|.|:
 Frog    25 INLLDNVVNCLYHGEG-AQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIK 88

  Fly    71 NSFSELPPHTHESLRDSLITHIGQIDEQTDNVIVTQLSLAVADLALLMAS---------WREPIN 126
            ..:..||.:..|.::..::..|  |...:|...|.:..:.:..|.:::..         |...|:
 Frog    89 TRWKILPRNQCEGIKKYVVGLI--IKTSSDATCVEKEKVYIGKLNMILVQILKQEWPKHWPTFIS 151

  Fly   127 DLLVTLAPHQCAIWPLLEVLKVLPEE-----------IDSRYLRLG-ANRREEVHKQLDASAECV 179
            |::......:......:.:||:|.||           :.:::|:.. .|...::.:
 Frog   152 DIVGASRTSESLCQNNMVILKLLSEEVFDFSSGQITQVKAKHLKDSMCNEFSQIFQ--------- 207

  Fly   180 LKFLCMCLQREDLDQQRVWNAALRT---YSAWLVIHAFPVSHVYNNAL-TQLAFRLLSLPETSGK 240
               ||..:. |:.....:.:|.|.|   :..|:     |:.:::...| :.|.::.|::|
 Frog   208 ---LCQFVM-ENSQNAPLVHATLETLLRFLNWI-----PLGYIFETKLISTLIYKFLNVP----- 258

  Fly   241 LHDNATECVCALLSCINTRQDGASDPESSFEAQ---LFGAVCM-------LETPYHLSVAH--ED 293
            :..|.:      |.|: |...|.|  .|.:|.|   ||....|       |.|...|:.::  :|
 Frog   259 MFRNVS------LKCL-TEIAGVS--VSQYEEQFVTLFTLTMMQLKQMLPLNTNIRLAYSNGKDD 314

  Fly   294 TDKTINYCRIFTSLCDAFFYDLLADAQKPHYSL--KGLDL--VLLCVGHF--------DYEVAEI 346
            ....|....:|  ||...         |.|..|  |.|:|  .|:...|:        :.|:.:|
 Frog   315 EQNFIQNLSLF--LCTFL---------KEHGQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKI 368

  Fly   347 TFHLWYKLSEDLFQRNEDKLTV-----------------LFRPHIERLISALFRHSQMESDHDGL 394
            ....|..|:.:|::.:....:.                 |:.|.:.::  .|...|:|....:.|
 Frog   369 CLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPVLSKV--RLLMVSRMAKPEEVL 431

  Fly   395 IEENNNFFDFRRKVSDLIKDVAFIVGSGACFKQMFHIL-----------------------QAPE 436
            :.||    |....|.:.:||...|    ..:|.|...|                       ...|
 Frog   432 VVEN----DQGEVVREFMKDTDSI----NLYKNMRETLVYLTHLDYADTERIMTEKLHNQVNGTE 488

  Fly   437 TTWESTEAALFIMQNVAKNI-LPDENEVIPKVVEAILNMSEQ-----THIAVRYTAILLIGELCD 495
            .:|::.....:.:.:::..: ..||...:..|::.:|.:.||     ....:....:.::|:...
 Frog   489 WSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPR 553

  Fly   496 WIENHPESLEAVLNFLL-YALQQKNGLAPAAAIALTSICSACRQKMVCHISGLVEIARSLDSFQI 559
            ::..|.:.|:.|:|.|. :..:..:|:...|......|...||:..|....|  |:...:|.
 Frog   554 FLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVG--EVMPFIDE--- 613

  Fly   560 NNDVAIGLLKGISLILTRLPREQLQPALREIVGFQLQPLAQLVDSTGSTPQKGERTDPV---YWI 621
                   :|..|:.|:..|..:|:. ...|.||:.:                |.:||..   :.|
 Frog   614 -------ILNNINTIICDLQPQQVH-TFYEAVGYMI----------------GAQTDQTVQEHLI 654

  Fly   622 DRAC--------AIIRHTNPDV-----PDNVE-----------------HPTVAILNDAWQLISR 656
            ::..        :||:....:|     |:.|:                 ||.|..|.   ::...
 Frog   655 EKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLG---RIYLD 716

  Fly   657 VMDKYQSDLRIMERTCRLIRYGIRMVRKQAMMLVEPLIKQMVVLYSVQHHSCFLYVGSILVDEFA 721
            :::.|:.   :.|.....|:....||.||      |||:.|   .:|:..:..|..|.:     :
 Frog   717 MLNVYKC---LSENISAAIQANGEMVTKQ------PLIRSM---RTVKRETLKLISGWV-----S 764

  Fly   722 KSSECIGGLLEML-QAFIEPTFG--LLQMENGL--KNNPDTVDDFFRLASRYLDCCPHQLLQSSL 781
            :||:     .:|: :.|:.|...  |:..:..:  ...|:.:.....:.::.......::.|  :
 Frog   765 RSSD-----PQMVAENFVPPLLDAVLIDYQRNVPAAREPEVLSTMATIVNKLGGHITAEIPQ--I 822

  Fly   782 ITPIFQCALIACSLDHREANSSVMKFFINLLVWGRSNNHSRNTECRPLVVELASQHGGALVMNLI 846
            ...:|:|.|...:.|..|.......||:.|        .:.|:.|.|..:.:....     ..|:
 Frog   823 FDAVFECTLNMINKDFEEYPEHRTNFFLLL--------QAVNSHCFPAFLAIPPAQ-----FKLV 874

  Fly   847 QASVFQLHSYMLVDVA----EVLHELKQVVGNE 875
            ..|:.....:.:.:||    ::|:.|.|.|..|
 Frog   875 LDSIIWAFKHTMRNVADTGLQILYTLLQNVAQE 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tnpo-SR	NP_001259961.1	IBN_N	28..94	CDD:281761	14/65 (22%)
		Xpo1	100..248	CDD:285575	26/172 (15%)
		HEAT repeat	427..454	CDD:293787	4/49 (8%)
		HEAT repeat	462..496	CDD:293787	5/38 (13%)
		HEAT repeat	506..531	CDD:293787	5/25 (20%)
xpo1	XP_002939551.2	CRM1	15..1044	CDD:227432	178/1008 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910