DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33514 and Ttpal

DIOPT Version :9

Sequence 1:	NP_001014558.1	Gene:	CG33514 / 3346239	FlyBaseID:	FBgn0053514	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_083788.2	Gene:	Ttpal / 76080	MGIID:	1923330	Length:	343	Species:	Mus musculus

Alignment Length:	306	Identity:	88/306 - (28%)
Similarity:	151/306 - (49%)	Gaps:	34/306 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LTPELQKVAKEQLKEDPERLEADLQAFKTWIEQQ-PHLNPRMDDQFLVAFLRGCKYSLERAKSKL 71
            ||.:|...|:|:|:|.||....|:||.:..:.:: |:|:..:||.||:.|||..|:..:||...|
Mouse    36 LTEDLVTKAREELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLL 100

  Fly    72 DKYYTLKTKYPDYFRVTNTTDSKFREIHQTGAIIYLPTPLNENGPRIGIWRMGLVP----VEKYT 132
            ..|:..:..:|:.|  :|...|..:::..:|.:..||    ...|| |...:.:.|    ...|.
Mouse   101 VNYHGCRRSWPEVF--SNLRPSALKDVLNSGFLTVLP----HTDPR-GCHVLCIRPDRWIPSNYP 158

  Fly   133 MLECMQVAQAMQEIAILEDDYANVNGVVFIMDMKGATAAHLFQMTPSMAKKFTVFSEEALPLRLK 197
            :.|.::......| .:::.:...|||:|.:.|.||.:.:......|.:|||.....::..|:|:|
Mouse   159 ITENIRAVYLTLE-KLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFPIRIK 222

  Fly   198 AQHFINTITGFEQLFNMFKPMMSKKMQSRLFVHGNKMGLLTEQIPLKYLPEEYGGENG-----TT 257
            |.|.:|....|:.:|.:.||.:.:|:.:|.|:||:.:..|...:|...||:||||..|     :.
Mouse   223 AVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRNILPKEYGGTAGELDTASW 287

  Fly   258 QDIVAAMEKKLDEYADFFQENVNF-----GTDESLRPGKPIDFEGL 298
            ..::.|.|:      ||.:|   |     ..|..|  |:|:..|||
Mouse   288 NAVLLASEE------DFVKE---FCQPMPACDNLL--GQPLLPEGL 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33514	NP_001014558.1	CRAL_TRIO_N	28..74	CDD:215024	16/46 (35%)
CG33514	NP_001014558.1	SEC14	97..253	CDD:238099	43/159 (27%)
Ttpal	NP_083788.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
		CRAL_TRIO_N	57..103	CDD:215024	16/45 (36%)
		SEC14	122..278	CDD:238099	43/161 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10174
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910