DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33514 and Sec14l5

DIOPT Version :9

Sequence 1:	NP_001014558.1	Gene:	CG33514 / 3346239	FlyBaseID:	FBgn0053514	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001121197.1	Gene:	Sec14l5 / 665119	MGIID:	3616084	Length:	696	Species:	Mus musculus

Alignment Length:	320	Identity:	54/320 - (16%)
Similarity:	109/320 - (34%)	Gaps:	85/320 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AKEQLKEDPERLEAD----------------LQAFKTWIEQQPHLNPRMDDQFLVAFLRGCKYSL 64
            |.|....|.::|:||                |...:.|: |:.|......|:.::.|||...:.|
Mouse   215 ASEMAIADGDKLDADYIERCLGHLSPMQESCLVQLRHWL-QETHKGKIPKDEHILRFLRARDFHL 278

  Fly    65 ERAKSKLDKYYTLKTKYPDYFRVTNTTDSKFREIHQTGAIIYL---PTPLNE-----------NG 115
            ::|:..|                  .....:|:.||...::..   |.||.|           :|
Mouse   279 DKARDML------------------CQSLSWRKQHQVDLLLQTWRPPPPLQEFYAGGWHYQDIDG 325

  Fly   116 PRIGIWRMGLVPVEKYTMLECMQVAQAMQEIAILEDDYA------------------NVNGVVFI 162
            ..:.|.|:|        .::...:.:|:.|.|:|:...:                  .::....:
Mouse   326 RPLYILRLG--------QMDTKGLMKAVGEEALLQHVLSVNEEGQKRCEGNTRQFGRPISSWTCL 382

  Fly   163 MDMKGATAAHLFQMTPSMAKKFTVFSEEALPLRLKAQHFINTITGFEQLFNMFKPMMSKKMQSRL 227
            :|::|....||::.......:.....|:..|..|.....:.....|..|:.:..|.:::..:.:.
Mouse   383 LDLEGLNMRHLWRPGVKALLRMIEVVEDNYPETLGRLLIVRAPRVFPVLWTLVSPFINENTRRKF 447

  Fly   228 FVHGNK----MGLLTEQIPLKYLPEEYGGENGTTQDIVAAMEKKL------DEYADFFQE 277
            .::...    .|.|.:.:....:|:..|||:.........:.|.|      .|.||..|:
Mouse   448 LIYSGSNYQGPGGLVDYLDKDVIPDFLGGESVCNVPEGGMVPKSLYLTEEEQEQADQLQQ 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33514	NP_001014558.1	CRAL_TRIO_N	28..74	CDD:215024	13/61 (21%)
CG33514	NP_001014558.1	SEC14	97..253	CDD:238099	28/191 (15%)
Sec14l5	NP_001121197.1	PRELI	17..173	CDD:368069
		CRAL_TRIO_N	243..288	CDD:215024	11/63 (17%)
		SEC14	306..479	CDD:214706	28/180 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900