DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33514 and Sec14l4

DIOPT Version :9

Sequence 1:	NP_001014558.1	Gene:	CG33514 / 3346239	FlyBaseID:	FBgn0053514	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001102560.1	Gene:	Sec14l4 / 498399	RGDID:	1565810	Length:	412	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	56/269 - (20%)
Similarity:	105/269 - (39%)	Gaps:	43/269 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSPQIRPLTPELQKVAKEQLKEDPERLEADLQAFKTWIEQQPHLNPRMDDQFLVAFLRGCKYSLE 65
            ||.|:..|:|:.|:.               |..|:..::......|:.||.||:.:||...:.|:
  Rat     1 MSGQVGDLSPQQQEA---------------LTRFREILQDVLPTLPKADDFFLLRWLRARNFDLK 50

  Fly    66 RAKSKLDKYYTLKTKYPDYFRVTNTTDSKFREIHQTGAII---YLPTP--------LNENGPRIG 119
            :::..|.|:...:.: .|...:......:...::.:|.:.   |...|        |:..|..:.
  Rat    51 KSEDMLRKHVEFRNQ-QDLDHILTWQPPEVIRLYDSGGLCGYDYEGCPVWFDLIGTLDPKGLFMS 114

  Fly   120 IWRMGL----VPVEKYTMLECMQVAQAMQEIAILEDDYANVNGVVFIMDMKGATAAHLFQMTPSM 180
            ..:..|    :.|.:..:.||...:|.:..         .|..:|.:.||:|.:..||::....:
  Rat   115 ASKQDLIRKRIKVCEMLLHECELQSQKLGR---------KVERMVMVFDMEGLSLRHLWKPAVEV 170

  Fly   181 AKKFTVFSEEALPLRLKAQHFINTITGFEQLFNMFKPMMSKKMQSRLFVHGN--KMGLLTEQIPL 243
            .::|....|...|..:|....|.....|...||:.|..:.:..|.::.:.|.  |..||....|
  Rat   171 YQQFFAILEANYPETVKNLIVIRAPKLFPVAFNLVKSFIGEVTQKKIVILGGNWKQELLKFMSP- 234

  Fly   244 KYLPEEYGG 252
            ..||.|:||
  Rat   235 DQLPVEFGG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33514	NP_001014558.1	CRAL_TRIO_N	28..74	CDD:215024	11/45 (24%)
CG33514	NP_001014558.1	SEC14	97..253	CDD:238099	37/173 (21%)
Sec14l4	NP_001102560.1	CRAL_TRIO_N	13..59	CDD:215024	12/60 (20%)
		SEC14	76..244	CDD:214706	37/178 (21%)
		GOLD_2	284..379	CDD:404736
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900