DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33514 and Sec14l1

DIOPT Version :9

Sequence 1:	NP_001014558.1	Gene:	CG33514 / 3346239	FlyBaseID:	FBgn0053514	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001101779.1	Gene:	Sec14l1 / 360668	RGDID:	1563123	Length:	720	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	50/280 - (17%)
Similarity:	108/280 - (38%)	Gaps:	57/280 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VAKEQLKEDPERLEAD----------------LQAFKTWIEQQPHLNPRMDDQFLVAFLRGCKYS 63
            ||:..:....::|:||                |...:.|: |:.|......|:.::.|||...::
  Rat   228 VAEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWL-QETHKGKIPKDEHILRFLRARDFN 291

  Fly    64 LERAKSKLDKYYTLKTKYP-DYFRVTNTTDSKFREIHQTGAIIYLPTPLNENGPRIGIWRMGLVP 127
            :::|:..:.:..|.:.::. ||...|.|.....::.:..|...:     :::|..:.:.|:|
  Rat   292 IDKAREIMCQSLTWRKQHQVDYILDTWTPPQVLQDYYAGGWHHH-----DKDGRPLYVLRLG--- 348

  Fly   128 VEKYTMLECMQVAQAMQEIAILEDDYA---NVNGV--------VF---------IMDMKGATAAH 172
                 .::...:.:|:.|.|:|.  |.   |..|:        ||         ::|::|....|
  Rat   349 -----QMDTKGLVRALGEEALLR--YVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRH 406

  Fly   173 LFQMTPSMAKKFTVFSEEALPLRLKAQHFINTITGFEQLFNMFKPMMSKKMQSRLFVH-GNKM-- 234
            |::.......:.....|...|..|.....:.....|..|:.:..|.:....:.:..:: ||..
  Rat   407 LWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQG 471

  Fly   235 -GLLTEQIPLKYLPEEYGGE 253
             |.|.:.|..:.:|:...||
  Rat   472 PGGLLDYIDKEIIPDFLSGE 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33514	NP_001014558.1	CRAL_TRIO_N	28..74	CDD:215024	11/61 (18%)
CG33514	NP_001014558.1	SEC14	97..253	CDD:238099	29/179 (16%)
Sec14l1	NP_001101779.1	PRELI	17..173	CDD:282550
		CRAL_TRIO_N	257..302	CDD:215024	9/45 (20%)
		CRAL_TRIO	327..491	CDD:279044	29/178 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810