DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33514 and Sec14l4

DIOPT Version :9

Sequence 1:	NP_001014558.1	Gene:	CG33514 / 3346239	FlyBaseID:	FBgn0053514	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_666125.1	Gene:	Sec14l4 / 103655	MGIID:	2144095	Length:	403	Species:	Mus musculus

Alignment Length:	285	Identity:	55/285 - (19%)
Similarity:	100/285 - (35%)	Gaps:	75/285 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSPQIRPLTPELQKVAKEQLKEDPERLEADLQAFKTWIEQQPHLNPRMDDQFLVAFLRGCKYSLE 65
            |..|:..|:|:.|:.               |..|:..::......|:.||.||:.:||...:.|:
Mouse     1 MRGQVGDLSPQQQEA---------------LARFRETLQDLLPTLPKADDYFLLRWLRARNFDLK 50

  Fly    66 RAKSKLDKYYTLKTKY------------------------------PDYFRVTNTTDSK--FREI 98
            :::..|.|:...:.:.                              |.:|.:..|.|.|  |...
Mouse    51 KSEDMLRKHVEFRNQQNLDQILTWQAPEVIQLYDSGGLSGYDYEGCPVWFDIIGTMDPKGLFMSA 115

  Fly    99 HQTGAIIYLPTPLNENGPRIGIWRMGLVPVEKYTMLECMQVAQAMQEIAILEDDYANVNGVVFIM 163
            .:...|          ..||.:..|        .:.||...:|.:..         .:..:|.:.
Mouse   116 SKQDMI----------RKRIKVCEM--------LLHECELQSQKLGR---------KIERMVMVF 153

  Fly   164 DMKGATAAHLFQMTPSMAKKFTVFSEEALPLRLKAQHFINTITGFEQLFNMFKPMMSKKMQSRLF 228
            ||:|.:..||::....:.::|....|...|..:|....|.....|...||:.|..|.::.|.::.
Mouse   154 DMEGLSLRHLWKPAVEVYQQFFAILEANYPETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIV 218

  Fly   229 V-HGNKMGLLTEQIPLKYLPEEYGG 252
            : .||....|.:.:....||.|:||
Mouse   219 ILGGNWKQELVKFVSPDQLPVEFGG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33514	NP_001014558.1	CRAL_TRIO_N	28..74	CDD:215024	11/45 (24%)
CG33514	NP_001014558.1	SEC14	97..253	CDD:238099	32/157 (20%)
Sec14l4	NP_666125.1	CRAL_TRIO_N	13..59	CDD:215024	12/60 (20%)
		SEC14	77..244	CDD:214706	38/194 (20%)
		GOLD_2	284..379	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810