Protein Alignment form3 and daam2

DIOPT Version :10

• Sequence 1: NP_001097527.1
• Gene: form3 / 3346238
• FlyBaseID: FBgn0053556
• Length: 1717
• Species: Drosophila melanogaster
• Sequence 2: XP_073783764.1
• Gene: daam2 / 798465
• ZFINID: ZDB-GENE-070709-1
• Length: 1103
• Species: Danio rerio
• Alignment Length: 1015
• Identity: 245/1015 - (24%)
• Similarity: 438/1015 - (43%)
• Gaps: 228/1015 - (22%)

  Fly     1 MDSRIGLDYIVENRDYIAKLGAALDTQNATVKKQVFELLSALCAYSPDGYARAIETLEFYKNLKK 65
            |::..|..:::.:...|..:..:|...|...|..|.|:|.|:|.. |||:.:.::.:..|:....
Zfish   185 MNNSQGRAHVLAHPQSINTISQSLHQDNIKTKVAVLEILGAVCLV-PDGHKKVLQAMAHYQKFAA 248

  Fly    66 QRYRFKIVINELELSSAAAHPPLDYQAALLAFINCVI---ISAATLQERIRIRNEFIGLKVLPLL 127
            :|.||:.::|.|:.|:......::.:.|:::|||.::   :...:::.|:.:|.||:.|.:.|::
Zfish   249 ERTRFQSLLNGLDRSTGHYRDEVNLKTAIMSFINAMLNAGVGEESIEFRLHLRYEFLMLGIQPVI 313

  Fly   128 NNLRLLEAGNVE---------------SSASPSPPPSLSSESASSATSPVSGSAS-TSVTPSPSP 176
            ..||..:...::               ..|.......:.::||......:....| |...|
Zfish   314 EKLRAHDNATLDRHLDFFEMVRNEDELELAKRFDSMHVDTKSAGQMFELIKKKLSHTDAYP---- 374

  Fly   177 LHLQRRLTFCGSLS-RYSCAALQLVQNLKKVAQSVGDIIVQLDVFVEQQECDEAQSLQAPDGINL 240
             ||...|..|..:. ::...::|..|.|.::.|.:                    .||..:|.|
Zfish   375 -HLLSILQHCLKMPYKHDAGSIQQWQLLDRILQQI--------------------VLQDENGEN- 417

  Fly   241 NSHLDVFYAILRQVADTPQEVPFLNI-LQHLLRIDPKEPLSDII-------W-DTTERL----VH 292
                             |...|..|. ::::::|..|..:|.::       | |..|:.    |.
Zfish   418 -----------------PDVSPLENFNVRNIIKIYGKRHMSRLVNENEVKQWRDQAEKFRKEHVE 465

  Fly   293 RATLLE-----------SHEDSVRLLR-------------TPSSQKFACQSCRGSDAS------- 326
            ..|.||           ..||.::.|.             ..:.::....|.|.||.|
Zfish   466 LMTRLERKDRECETKTQEKEDMMKTLNKMKDKLQREGVELRSAKEQVLDMSSRISDISYVGVPLP 530

  Fly   327 ---------SPTRKPSQPV--GVSAKTTPPPPPPPMAPAAPPPPPPPINGAAPP--PPPPPMING 378
                     .|...||.|:  |.|....|||||||..|...||||||     ||  ||.||....
Zfish   531 FPHPLPGSPMPPPPPSPPIMLGGSPLLFPPPPPPPPPPLLHPPPPPP-----PPLLPPLPPSFAF 590

  Fly   379 GALPPPPPPPSMQMASRPRTPDPL--------AAEAVATAILLPQ-QDTPAPKAKMKTINWGKIP 434
            .:.||||||||......|....|:        |:.:..|:   || :..|.|...:|:.||.|:.
Zfish   591 SSPPPPPPPPSFGCPQPPPGAPPIFSGIPPGPASNSSTTS---PQTKSIPQPSQPLKSFNWSKLG 652

  Fly   435 HNKVLGKQNIWSIVASNHQDSPMQDIDWNEMEGLFCLQTASAQGSPKLGRDGSQAAAGSNGCDTL 499
            .|::  ...||..:....   ..:.:|..::|.:|     ||.       ...|...||  .|.|
Zfish   653 GNEI--TDTIWYGIDDRR---AFKVLDLKDIEKMF-----SAY-------QRQQKETGS--MDDL 698

  Fly   500 DRKSKKESTEITLLDGKRSLNVNIFLKQFRTSNDDIIQ-LIRQGAHEEIGAERLRGLLKIMPEVD 563
            :..::|.. |::::||:|:.|..|.|.:.:.||:::.: ::.....||:..:.|..|||.:||..
Zfish   699 NLSARKVK-ELSVIDGRRAQNCVILLSKLKMSNEELKRAVLEMDEREELAKDMLEQLLKFVPEKS 762

  Fly   564 ELDMLKGFNGDKARLGNAEKFLLQLLEVPNYKLRIESMLLKEEFAANVAYLEPCINSMLYAGDDL 628
            ::|:|:....:..|:..|::||.::..:.:|:.|::|:..|::||..:|..:|...::|.|..::
Zfish   763 DMDLLEEHKHELERMARADRFLFEMSRIDHYQQRLQSLFFKKKFADRLAETKPKAEAILCASREV 827

  Fly   629 LNNKTLQEVLYMVVVAGNFLNSGGYAGNAAGVKLSSLQKLTDIRAN-KPGMNLIHFVALQAEKRN 692
            :.:|.|::||.:|:..|||:|. |..|||.|.|:|||.|:.|.::: ...:.::|::.:..||..
Zfish   828 MRSKLLRQVLEVVLAFGNFMNK-GQRGNAYGFKVSSLNKIIDTKSSIDRNITMLHYLIMIFEKNY 891

  Fly   693 PELLQFTGQLSNLESASKTTSEQINNEINTLDGRIRRIARQIEQPATDVDIKEQ----------- 746
            |::|.....|.::..|:|....::..|::::...::         |.:|:::.|
Zfish   892 PDILSIQQDLCSVSEAAKVNLAELEKEVSSIRSGLK---------ALEVELRYQQSRVCDRGDKF 947

  Fly   747 ---MADFLQAAE---SELSVLQAGMKQVESMRLKMSEFFCDDAATFRLEECFKIFHNFCDKFKQA 805
               ::||:..|.   |||..|....|...||.||   .|.::....:.:|.|.||..|...|.:|
Zfish   948 VPVVSDFITVASFSFSELEELLNEAKDKFSMALK---HFGEEEGRMQPDEFFGIFDIFLQSFSEA 1009

  Fly   806 VKE--NERRQQQEQQATLR-----RKQREEQLARRARQIGQAGTPVSDSEHSFLGDAIFDPRASP 863
            ..:  |.:|.::|::..:|     :.|||.:  |||::    ||..|.||.  :|:  ||...|.
Zfish  1010 RHDLKNMQRCKEEEERKIRLEAMLKDQRERE--RRAKK----GTKGSVSEE--VGE--FDDLVSA 1064

  Fly   864 ALSRRHLGSGEISNGFIRLEQDGASPDITPNGSLRRRRSR 903
                  |.|||:      .::|         ..|:|.|.|
Zfish  1065 ------LRSGEV------FDKD---------SKLKRNRKR 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
form3	NP_001097527.1	Drf_FH3	48..309	CDD:461885	55/317 (17%)
		FH2	415..803	CDD:396655	104/407 (26%)
		PTZ00449	<1145..1465	CDD:185628
daam2	XP_073783764.1	None