Protein Alignment form3 and Fmn1

DIOPT Version :10

• Sequence 1: NP_001097527.1
• Gene: form3 / 3346238
• FlyBaseID: FBgn0053556
• Length: 1717
• Species: Drosophila melanogaster
• Sequence 2: XP_038962394.1
• Gene: Fmn1 / 296512
• RGDID: 1306349
• Length: 1429
• Species: Rattus norvegicus
• Alignment Length: 876
• Identity: 198/876 - (22%)
• Similarity: 322/876 - (36%)
• Gaps: 233/876 - (26%)

  Fly   142 ASPSPPPSLSSESASSAT------------SPVSGSAST-----SVTPSPSPLHLQRRLTFCGSL 189
            ||| |.|.|..|.....:            ||......|     :|.|.|.....:.::....:.
  Rat   659 ASP-PCPFLLHEDKEKTSRSELYLDLNPDQSPTEQDDRTPGRLQAVWPPPKTKDTEEKVGLKYTE 722

  Fly   190 SRYSCAALQL-------VQNLK-------------------KVAQSVGDIIVQLDVFVEQQECDE 228
            :.|..|.|.|       ::||:                   ::.:::.::..||:  ..:.||:|
  Rat   723 AEYQAAILHLKREHKEEIENLQAQFELKTFHIRGEHALVTARLEETIDNLKQQLE--KRRGECEE 785

  Fly   229 AQSLQAPDGINLNSHLDVFYAILRQVADTPQEVPFLNILQHLLRIDPKEPLSDIIWDTTERLVHR 293
            .:.      :.:::..|.|....|.|........||....    ::.|...|..|  ..::|...
  Rat   786 MRD------VCVSTDDDCFPKAFRNVCIQTDRETFLKPCD----VESKTTRSSQI--VPKKLTIS 838

  Fly   294 ATLLESHEDSVRL---LRT----PSS--QKFACQSCRGSDASSPTRKPSQPVGVSAKTTPPPPP- 348
            .|.|...:||...   |:|    |||  ||.       |..:.||..|..|:       |||||
  Rat   839 LTQLSPSKDSKDFHAPLQTRECIPSSSQQKI-------SPPAPPTPPPPPPI-------PPPPPL 889

  Fly   349 ----------PPMAPAA--------PPPPPPPI---NGAAPPPPPPPMIN-------GGALPPPP 385
                      ||::|.:        |||||||:   .|..|||||||:.|       ||..||||
  Rat   890 PPGLGPLPPAPPISPVSAGSPLPPPPPPPPPPLPPSAGPPPPPPPPPLPNVQTPPNSGGPPPPPP 954

  Fly   386 PPPSMQMASRPRTPDPLAAEAVATAILLPQQDTPAPKAKMKTINWGKIPHNKVL--GKQNIWSIV 448
            |||...:|  |..|..|:....:::...|::....|...||.:.|.:|..|...  ....:|..:
  Rat   955 PPPPPGLA--PPPPPGLSFGLSSSSSQCPRKPAIEPSCPMKPLYWTRIQINDKSQDATPTLWDSL 1017

  Fly   449 ASNHQDSPMQDIDWNEMEGLFCLQTASAQGSPKLGRDGSQAAAGSNGCDTLDRKSKKESTEITLL 513
            ...|      .:|.:|.|.||...|...:..|.              .:..::|:|.:.. |.||
  Rat  1018 EEPH------IMDTSEFEYLFSKDTTQQKKKPL--------------SEAYEKKNKVKKI-IKLL 1061

  Fly   514 DGKRSLNVNIFLKQFRTSNDDIIQLIRQGAHEEIGAERLRGLLKIMPEVDELDMLKGF-----NG 573
            |||||..|.|.:........||.|.|.......:..|.|..|.:...:.|||..::.:     ..
  Rat  1062 DGKRSQTVGILISSLHLEMKDIQQAIFNVDDSVVDLETLAALYENRAQEDELTKIRKYYETSREE 1126

  Fly   574 DKARLGNAEKFLLQLLEVPNYKLRIESMLLKEEFAANVAYLEPCINSMLYAGDDLLNNKTLQEVL 638
            |...|...|:||.:|.::||:..|.:.::.:..|:..:..|...:..:..|...||:.|:::::|
  Rat  1127 DLKLLDKPEQFLHELAQIPNFAERAQCIIFRAVFSEGITSLHRKVEIVTRASKGLLHMKSVKDIL 1191

  Fly   639 YMVVVAGNFLNSGGYA-GNAAGVKLSSLQKLTDIRANKPGMNLIHFVALQAEKRNPELLQFTGQL 702
            .:::..||::|.|... |.|.|..|..|.||.|:::...||||:.:|.       ...|::..|.
  Rat  1192 ALILAFGNYMNGGNRTRGQADGYSLEILPKLKDVKSRDNGMNLVDYVV-------KYYLRYYDQE 1249

  Fly   703 SNLES-------------ASKTTSEQINNEINTLDGRIRRIARQIEQPATDVDI--KEQMADFLQ 752
            :..:.             ||:...|.:..:       :|::.||:|.....:.:  ||...::||
  Rat  1250 AGTDKSVFPLPEPQDFFLASQVKFEDLIKD-------LRKLKRQLEASEQQMRLVCKESPREYLQ 1307

  Fly   753 AAESELSVLQAGMKQVESMRLKMSEFFCDDAATFRLEECFKIFHNFCDKFKQAVKENERRQQQEQ 817
            ..:.                 |:.||                       ||:|.||::..:...:
  Rat  1308 PFKD-----------------KLEEF-----------------------FKKAKKEHKMEESHLE 1332

  Fly   818 QATLRRKQREEQLARRARQIGQAGTPVSDSEHSFLGDAIFD-------------PRASPALSRRH 869
            .|   :|..|       ..:|..|......|.......:|.             .|.|..:|:..
  Rat  1333 NA---QKSFE-------TTVGYFGMKPKTGEKEVTPSYVFMVWFEFCSDFKTIWKRESKNISKER 1387

  Fly   870 LGSGEISNGFIRLEQDGASPDITPNGSLRRR 900
            |...|.|...:..|:...:..|.|..||:.|
  Rat  1388 LKMAEASVSKLTSEKKVETKKINPTASLKER 1418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
form3	NP_001097527.1	Drf_FH3	48..309	CDD:461885	39/212 (18%)
		FH2	415..803	CDD:396655	86/410 (21%)
		PTZ00449	<1145..1465	CDD:185628
Fmn1	XP_038962394.1	FH2	983..1380	CDD:214697	99/481 (21%)