Protein Alignment nab and nab1b

DIOPT Version :10

• Sequence 1: NP_001014557.3
• Gene: nab / 3346237
• FlyBaseID: FBgn0259986
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001116745.1
• Gene: nab1b / 564685
• ZFINID: ZDB-GENE-081105-85
• Length: 500
• Species: Danio rerio
• Alignment Length: 557
• Identity: 180/557 - (32%)
• Similarity: 258/557 - (46%)
• Gaps: 110/557 - (19%)

  Fly   113 PGNEAEVQLYRVLQRASLLAYYDTLLEMGGDDVQQLYDAGEEEFLEIMALVGMASKPLHVRRLQK 177
            |....|:||||:||||:||.|||..::.||||||||.:|||:|||||||||||||||||||||||
Zfish     6 PRTLGELQLYRILQRANLLCYYDAFIQQGGDDVQQLCEAGEDEFLEIMALVGMASKPLHVRRLQK 70

  Fly   178 ALHEWANNPGLFQGPMMPHLGLCETPPKPALIFN-PDTTPALPRQKFPSFNPSGSSFMPSPVPPA 241
            ||.:|..||.||..| :..|.:|..|     ::. |:.:|.|    .|.....|.:.:.   .|.
Zfish    71 ALRDWVTNPALFNQP-LTSLPVCSIP-----VYKLPEGSPTL----LPGNGARGDTQVK---VPK 122

  Fly   242 PLPASASVPAPTVPLATQISCPSAPSVPLPLVLPPNPLTSSPHPSANSNLPANTAHQV------S 300
            .|.||...|....|    .:..|:.:|        :||.|...|...:|....:.|.:      |
Zfish   123 CLAASCVDPGKGEP----GNGNSSATV--------SPLQSGSEPRFWANHGTESEHSLSPAELGS 175

  Fly   301 SSSPQ-LTPVLTEAQIQRITMCADKIGRQLPQREPRAQTTRKRTTRELEQVIA----MGEQDPRR 360
            .|||: ....|..|.:|.:..|.::|.:.||:.:|.....:.:..::|.::|:    |.|:||.|
Zfish   176 PSSPRDGLEALDAAAVQSVAECVERITQTLPKSDPTEVKDQLKGNKKLAKMISHIFDMSEEDPHR 240

  Fly   361 MDEIRKYSAIYGRFDCKRRPEKPLTLHEVCVNEAAAQLCRNPQTIWLLTRRDELFPLARQIVKDA 425
            .:|||||||||||||.||:..|.|||||:.|||||||||.  :.:.|||||||||.||||:.::.
Zfish   241 EEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCM--KEVALLTRRDELFGLARQVSREV 303

  Fly   426 GFGHS--ASIARYGGLLTQLPSQGAGLGGGRAPGDTDC--------------ESSDAAVPSKRQR 474
            .:.::  .|.:|.|......|.        |...:..|              |:....:...|.:
Zfish   304 TYKYTYRTSKSRCGDRDEPSPK--------RIKTEEGCFDLQEALQAIHMRQETLKEQLAHARSK 360

  Fly   475 LSSTEAAQLPLDLNR------EAVED--SRYNLFAMYQKFAKPPFDLSEIAKFSVSKAADYEDND 531
            ...|....:.:.|.|      |.:.|  ::..|.|:..:....|:          ..:|| ..|.
Zfish   361 GEETLGRNIQVQLERLLAKQMEILHDAAAQDRLQALEWRVPPGPY----------KHSAD-RQNS 414

  Fly   532 SRFSFSNSSSPTMPTPCN--------GMEGERSPVSRQMETSSPPRESVDLSGTSSGAALSGVQV 588
            :..:...::.|....|.|        .:....:|:.:|:..........:.....|.|..:|
Zfish   415 NGLTADKNTEPQGERPLNLRVTNQRTSISDGDTPLGKQLANELKRHHHANAENKMSAATENG--- 476

  Fly   589 ISAAGDNIIAVANPALALSPALNEVLALKRSAAS-PE 624
                ||          |.|.|||  |:.|::..| ||
Zfish   477 ----GD----------ASSRALN--LSEKKTIKSEPE 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nab	NP_001014557.3	NCD1	113..190	CDD:461473	55/76 (72%)
		NCD2	309..435	CDD:461474	59/131 (45%)
nab1b	NP_001116745.1	NCD1	5..83	CDD:461473	55/76 (72%)
		NCD2	185..313	CDD:461474	58/129 (45%)
		Nab1	317..499	CDD:461472	37/219 (17%)