Protein Alignment nab and mab-10

DIOPT Version :10

• Sequence 1: NP_001014557.3
• Gene: nab / 3346237
• FlyBaseID: FBgn0259986
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_496268.2
• Gene: mab-10 / 187916
• WormBaseID: WBGene00003107
• Length: 582
• Species: Caenorhabditis elegans
• Alignment Length: 606
• Identity: 187/606 - (30%)
• Similarity: 257/606 - (42%)
• Gaps: 178/606 - (29%)

  Fly     1 MEASSNPTTPTTAVATTTSTSSPSPAASTSSKGHSQSATASASASATQSQLLTTSLEMPKTEDLY 65
            |.:||:.:.||::.:||||:.:..|:||    .|.:|..:|:|:|.:....||       |:...
 Worm     1 MSSSSSSSLPTSSASTTTSSITSRPSAS----HHLESILSSSSSSPSILSSLT-------TQSTS 54

  Fly    66 NLSVASGLSEGQRSLSGAP-SASSSPIMSPQGKIFGRNANGTMITTSRPGNEAEVQLYRVLQRAS 129
            ::..:|..|..::|.|.|. ..|..|:.:|              ||.     :|.||..||.:|:
 Worm    55 SIPTSSSSSSQRQSTSNADRPVSPKPMPTP--------------TTL-----SEWQLLAVLSKAN 100

  Fly   130 LLAYYDTLLEMGGDDVQQLYDAGEEEFLEIMALVGMASKPLHVRRLQKALHEWANNPGLFQGPMM 194
            |:.|||..:..||||:.|:....|.||||||.||||..|||||||:|:||.|::.:...|....:
 Worm   101 LVQYYDVFIAQGGDDINQIMACEEREFLEIMNLVGMLPKPLHVRRMQRALAEYSQDQTAFNLAAL 165

  Fly   195 PHLGLCETPPKPALIFNP---------------DTTPALPRQKF--------------------- 223
            ..:|     |.|.|.:.|               .|:|..|..:|
 Worm   166 QQIG-----PPPPLNYTPAGTDPMALLLPGIAAATSPKFPSLRFLSQLSSVAEKVSTPSEAADTS 225

  Fly   224 ---PSFN---------------------------------------PSGSSFMPSP-VPPAPLPA 245
               ||.|                                       ||.||....| :|...|||
 Worm   226 SSSPSLNLNTTSSNSVPLAFKFSTPLLESLASDQQSSSTSSVRSVLPSTSSNTSHPELPAGILPA 290

  Fly   246 -----SASVPAPTVPLATQI--------SCPSAPSVPLPLVLPPNPLTSSPHPSANSNLPANTAH 297
                 ||:||.|:......:        :...|.||...||:||:. ||...||.:....::...
 Worm   291 TTTNVSAAVPPPSSRATANVFSGNSIGLNFSGAASVTRHLVVPPSS-TSIQQPSTSFGRSSSITG 354

  Fly   298 Q--VSSSSPQL---------------------------TPVLTEAQIQRITMCADKIGRQLPQRE 333
            |  ..||||.|                           .|.|:.|||.|:..||....:.||...
 Worm   355 QEKEGSSSPFLGVGYSQPYGNDFVSLGDFDPNNPSLTENPTLSTAQISRLAECALAASKNLPPLP 419

  Fly   334 PRAQTTRKRTTRELEQVIAMGEQDPRRMDEIRKYSAIYGRFDCKRRPEKPLTLHEVCVNEAAAQL 398
            ||....:||.::|:.:::......|..:...|||||||||||.||:|.|.|||||..||||||||
 Worm   420 PRLVQNKKRVSKEVIELLKCSPATPSMIHAFRKYSAIYGRFDTKRKPHKVLTLHETTVNEAAAQL 484

  Fly   399 CRNPQTIWLLTRRDELFPLARQIVKDAGFGHSASIARYGGLLTQLPSQGAGL-----GGGRAPGD 458
            |....:  ||||||||||||||||||||:.::.|..|        |...|.|     ..|.:|..
 Worm   485 CLLVPS--LLTRRDELFPLARQIVKDAGYNYAKSRKR--------PCDPADLHSPISSPGNSPPP 539

  Fly   459 TDCE-----SSDAAVPSKRQR 474
            .:.|     ||.:....:.:|
 Worm   540 QESEFDEQPSSSSGAFKEEER 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nab	NP_001014557.3	NCD1	113..190	CDD:461473	37/76 (49%)
		NCD2	309..435	CDD:461474	65/125 (52%)
mab-10	NP_496268.2	NCD1	83..161	CDD:461473	40/96 (42%)
		NCD2	395..519	CDD:461474	65/125 (52%)