DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and nptn

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_012822135.1	Gene:	nptn / 733721	XenbaseID:	XB-GENE-1011670	Length:	407	Species:	Xenopus tropicalis

Alignment Length:	270	Identity:	54/270 - (20%)
Similarity:	93/270 - (34%)	Gaps:	94/270 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 PRNITTRTGHTAAINCRVDNLGDKSVSW-----------------IRKRDLHILTA----GILTY 156
            |.:.|..||....:.|.|.......:.|                 .|||.:.|..|    |:.
Frog    40 PMSETKLTGDAFELYCEVVGYPTPEIQWWYAEVNRAESFKQLWDGARKRRVTIGAAYGANGVS-- 102

  Fly   157 TSDERFKVVRTADSKDWTLHVKYAQPRDSGIYECQVNTEPK------------ISMAFRLNVIVT 209
                             .|.:......|||.|||:.:.:|:            |.....::|::.
Frog   103 -----------------VLRITRLTLEDSGTYECRASNDPRRNDLRQNPAMTWIRAQATVSVLLK 150

  Fly   210 PPDAKAIIAGPTDLYVKVGSSVT---LTCHVKQPATSAQ-DIGPIYWYRGPYILTPFVAHPNDAA 270
            |.     |:...::.:|..::.|   |.|::  ..||:| ::..:||.:            |...
Frog   151 PK-----ISATEEITIKKDTTPTPIFLQCNL--TVTSSQGELESVYWTK------------NGLE 196

  Fly   271 I-DLQRISMESTLAEKLQSRLRIANAQLLDTGNYTCMPTTAEAASVVVNVINDESPA-AMQKSRA 333
            : |.::.|.|..:      .|:||..:..|:|.|.|          |....|:..|| |..:.:|
Frog   197 VQDTRKNSPEFVM------ELKIAKPKADDSGEYMC----------VFTFKNNSPPANATIEVKA 245

  Fly   334 I-RTSGSMRS 342
            : ..||..:|
Frog   246 VPEISGHKKS 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	22/125 (18%)
		Ig	116..192	CDD:299845	19/96 (20%)
		ig	220..306	CDD:278476	19/90 (21%)
		IG_like	220..306	CDD:214653	19/90 (21%)
nptn	XP_012822135.1	Ig	51..124	CDD:319273	16/91 (18%)
		Ig	<190..238	CDD:386229	15/75 (20%)
		Ig	259..342	CDD:386229
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910