DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and Sirpb1b

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_006530146.1	Gene:	Sirpb1b / 668101	MGIID:	3779828	Length:	408	Species:	Mus musculus

Alignment Length:	148	Identity:	37/148 - (25%)
Similarity:	57/148 - (38%)	Gaps:	35/148 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 IIAGPTDLYVKVGSSVTLTCHVKQPATSAQDIGPIYWYRG----PYILTPFVAHPNDAAIDLQRI 276
            :|......:|..|.|.||.|.|    ||...:|||.||||    ..::..|...      ...||
Mouse    33 VIQPVKSFFVGAGGSATLNCTV----TSLLPVGPIRWYRGVGQSRLLIQSFTGE------HFPRI 87

  Fly   277 SMESTLAEK--LQSRLRIANAQLLDTGNYTCMPTTAEAASVVVNVINDESPAAMQKSRAIRTSGS 339
            :..|.:.::  |...:||:|....|:|.|.|:..               ...:.:..|.|::.|.
Mouse    88 TSVSDVTKRNNLDFSIRISNVTPADSGTYYCVKF---------------QRGSSESDREIQSGGG 137

  Fly   340 MRSSRLVLLLAMVASSVV 357
            ...|    :||..:|.:|
Mouse   138 TELS----VLAKPSSPMV 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653
		Ig	116..192	CDD:299845
		ig	220..306	CDD:278476	27/91 (30%)
		IG_like	220..306	CDD:214653	27/91 (30%)
Sirpb1b	XP_006530146.1	Ig	32..143	CDD:386229	33/138 (24%)
		IgC_SIRP_domain_2	145..248	CDD:319314	2/7 (29%)
		IgC_SIRP_domain_3	250..352	CDD:319334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	41	1.000	Domainoid score	I12440
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000