DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr2 and Btnl6

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_109672.1	Gene:	Btnl6 / 624681	MGIID:	1932038	Length:	539	Species:	Mus musculus

Alignment Length:	324	Identity:	70/324 - (21%)
Similarity:	104/324 - (32%)	Gaps:	84/324 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 FGMPRNITTRTGHTAAINC------RVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFKVVRTA 168
            ||....|....|..|.:.|      .|:|:  :.:.|.|.|    .:|.:|.|...|..|..:..
Mouse    34 FGPSDPIVAAPGGEAILPCSVIPAMNVENM--EELRWFRSR----FSAAVLVYRDQEEQKREQLP 92

  Fly   169 DSKDWTLHVK-------------YAQPRDSGIYECQ----VNTEPKISMAFRLNVIVTPPDAKAI 216
            :....|..||             ..|..|||||.|.    |..|..|   ..|.|.......:..
Mouse    93 EYSQRTSLVKEQFHQGTAAVRILNVQAPDSGIYICHFKQGVFYEEAI---LELKVAAMGSVPEVY 154

  Fly   217 IAGPTDLYVKVGSSVTLTCHVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMEST 281
            |.||.|      ..|.:.|     .||.       ||..|.:      |..|:..:....|:| .
Mouse   155 IKGPED------GGVCVVC-----ITSG-------WYPEPQV------HWKDSRGEKLTASLE-I 194

  Fly   282 LAEKLQSRLRIANAQLL---DTGNYTCM---PTTAEAASVVVNV-------INDESPA-----AM 328
            .:|..|...|...:.::   ...|.||.   |...:..::.:.:       ::...||     .|
Mouse   195 HSEDAQGLFRTETSLVVRDSSVRNVTCSTFNPILGQEKAMAMFLPEPFFPKVSPWKPAFFVTLTM 259

  Fly   329 QKSRAIRTSGSMRSSRLVLLLAMVASSVVRWLIGG-QRIGSNSC-HDSCSNLSTLHINYCNLRA 390
            .....:.||...|..|...|       :|:.|.|. ||:..|.. .|:...:..|.:.....:|
Mouse   260 MGLLVLGTSYLFRRERSARL-------IVQELTGNLQRVEDNKAEEDTVRTIDALMVELAQRKA 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	28/115 (24%)
		Ig	116..192	CDD:299845	24/98 (24%)
		ig	220..306	CDD:278476	18/88 (20%)
		IG_like	220..306	CDD:214653	18/88 (20%)
Btnl6	NP_109672.1	Ig	45..145	CDD:386229	27/108 (25%)
		Ig	150..232	CDD:386229	22/106 (21%)
		SPRY_PRY_C-I_1	341..503	CDD:293968
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910