DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and nitr2b

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_571724.1	Gene:	nitr2b / 60647	ZFINID:	ZDB-GENE-001106-6	Length:	313	Species:	Danio rerio

Alignment Length:	204	Identity:	44/204 - (21%)
Similarity:	70/204 - (34%)	Gaps:	47/204 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 LYVKVGSSVTLTC-HVKQPATSAQDIGPIYWYRGPYILTPFV----------AHPNDAAIDLQ-R 275
            :.|:.|.:|.||| ..|:..||      :.|.:......|.:          .:.||  .|.| |
Zfish    29 MIVQAGVAVNLTCIFPKESRTS------VVWVKQRVGEKPLLIASAYQGLAGKYEND--FDKQNR 85

  Fly   276 ISMESTLAEKLQSRLRIANAQLLDTGNYTCMPTTAE-----AASVVV-----NVINDESPAAMQK 330
            ..:|.   ::....|.|||.::.||..|.|:....|     :..::|     |:.::...:|.:.
Zfish    86 FFIEK---DEGSFNLSIANTEISDTATYYCVAYVYEFIFGNSTDLIVNAGKLNIKSEHQRSASED 147

  Fly   331 SRAIRTSGSMRSSRLVLLLAMVASSVVRWLIGGQRIGSNSCHDSCSNLSTLH------------- 382
            .:....|.|......|......:......:|..|...|..|..|....||.|
Zfish   148 QQCSVISQSCAEEHKVYWFRQGSGESSPGVIYTQNSRSAQCEKSSDLNSTAHKCIYSLPKTDEDP 212

  Fly   383 -INYCNLRA 390
             |.||.:.|
Zfish   213 AIYYCAVAA 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653
		Ig	116..192	CDD:299845
		ig	220..306	CDD:278476	24/94 (26%)
		IG_like	220..306	CDD:214653	24/94 (26%)
nitr2b	NP_571724.1	IG_like	28..129	CDD:214653	26/110 (24%)
		IgV	29..129	CDD:143167	26/110 (24%)
		Ig	149..232	CDD:299845	15/73 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1457433at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010