DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr2 and cadm2b

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_005157530.1	Gene:	cadm2b / 571698	ZFINID:	ZDB-GENE-080506-3	Length:	441	Species:	Danio rerio

Alignment Length:	202	Identity:	56/202 - (27%)
Similarity:	85/202 - (42%)	Gaps:	30/202 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 FGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFKVVRTADSKDWT 174
            |.:.:|:|...|.||.:.||||...:.|:.|..... ..|..|......|.|.::|| |..|:.|
Zfish    35 FPITQNVTVVEGSTANMTCRVDYNDNTSLQWSNPAQ-QTLFFGDKKALRDNRIELVR-ASWKELT 97

  Fly   175 LHVKYAQPRDSGIYECQVNTEP-KISMAFRLNVIVTPPDAKAIIAG---PTDLYVKVGSSVTLTC 235
            :.:......|.|.|.|.:.|.| |.|.|| |.|:..|  ||..|.|   |    .:.|..|||||
Zfish    98 ISISDVALSDEGQYTCSLFTMPVKTSKAF-LTVLGVP--AKPEITGLSRP----AQEGEDVTLTC 155

  Fly   236 HVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMEST-LAEKLQSRLRIANAQLLD 299
                ..:.::....|.|:|            ||..:...:..:.:| .:..::|.:.:...:..|
Zfish   156 ----TTSGSKPAADIRWFR------------NDKEVQAGQKEVNATGRSFTVRSSVHLKVDRKDD 204

  Fly   300 TGNYTCM 306
            ...|||:
Zfish   205 GAAYTCV 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	31/93 (33%)
		Ig	116..192	CDD:299845	23/75 (31%)
		ig	220..306	CDD:278476	17/86 (20%)
		IG_like	220..306	CDD:214653	17/86 (20%)
cadm2b	XP_005157530.1	Ig	35..129	CDD:299845	32/96 (33%)
		IG_like	39..129	CDD:214653	31/92 (34%)
		Ig	151..230	CDD:299845	16/77 (21%)
		I-set	234..320	CDD:254352
		IGc2	247..310	CDD:197706
		4.1m	363..381	CDD:128590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910