DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and cntn4

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001073520.1	Gene:	cntn4 / 571349	ZFINID:	ZDB-GENE-060929-776	Length:	1028	Species:	Danio rerio

Alignment Length:	208	Identity:	51/208 - (24%)
Similarity:	83/208 - (39%)	Gaps:	44/208 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 PRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFKVVRTADSKDWTLHV 177
            |:::......:....|:.......|..|::.        |.....::||.:|:..|      |.:
Zfish   325 PQDVQKPIDDSLVWECKATGKPKPSYRWMKN--------GENLEPTEERVQVINGA------LSI 375

  Fly   178 KYAQPRDSGIYECQV-NTEPKISMAFRLNVIVTPPD-AKAIIAGPTDLYVKVGSSVTLTCHVKQP 240
            .:....|.|:|:|.. |...::.....|.||...|| ::..:...|  .||.|..|.:.|   :|
Zfish   376 THLALSDIGMYQCVAGNKYGEVYSNAELRVIAVAPDFSQNQLKSHT--LVKEGGDVLIEC---KP 435

  Fly   241 ATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRIS-MESTLAEKLQSRLRIANAQLLDTGNYT 304
            ..|.:  |.|.|.:|           |||..:..||: :||       ..|||:|....|.|:||
Zfish   436 KMSPR--GSISWRKG-----------NDALRESSRIAVLES-------GSLRISNVSKSDAGSYT 480

  Fly   305 CMPTT--AEAASV 315
            |:...  .||:|:
Zfish   481 CVARNQFGEASSL 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	16/93 (17%)
		Ig	116..192	CDD:299845	13/75 (17%)
		ig	220..306	CDD:278476	27/86 (31%)
		IG_like	220..306	CDD:214653	27/86 (31%)
cntn4	NP_001073520.1	I-set	26..118	CDD:254352
		Ig	26..116	CDD:299845
		Ig	121..216	CDD:299845
		IG_like	131..207	CDD:214653
		Ig	228..316	CDD:299845
		I-set	228..309	CDD:254352
		I-set	319..405	CDD:254352	16/93 (17%)
		Ig	320..405	CDD:299845	16/93 (17%)
		I-set	410..498	CDD:254352	33/109 (30%)
		Ig	426..498	CDD:299845	28/91 (31%)
		I-set	504..597	CDD:254352
		Ig	517..601	CDD:299845
		FN3	601..693	CDD:238020
		FN3	707..799	CDD:238020
		FN3	808..901	CDD:238020
		FN3	893..994	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910