DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and igsf9bb

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	288	Identity:	60/288 - (20%)
Similarity:	103/288 - (35%)	Gaps:	76/288 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 PSSIDNDYVYIASVNRKFPQFGNSIDDER-EAEEQPPEE---------------------TTYPP 105
            |..:|.:|...||::.|     :|:..|| .:|:|...|                     |...|
Zfish    77 PPHVDPEYAGRASLHGK-----SSLRIERVRSEDQGWYECKVLMLEQQYHTFHNGSWVHLTVNAP 136

  Fly   106 PVFDFGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFKVVRTADS 170
            |.|....|:.:..:.|.:..::|........||||:|:.:         ......::||
Zfish   137 PTFTDTPPQYVEAKEGGSITLSCTAFGNPKPSVSWLREGN---------PVQDSTKYKV------ 186

  Fly   171 KDWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGPTDLYVKVGSSVTLTC 235
            .|.:|.:......|.|.|.|:..:|...::.....::..||   .|::.|.::.|.:......||
Zfish   187 SDGSLTLVSISREDRGAYTCRAYSEQGEAVHTTRLLVQGPP---FIVSPPENITVNISQDAFFTC 248

  Fly   236 HVKQPATSAQDIGPIYWYRGPYILTPF-----VAHPNDAAIDLQRISMESTLAEKLQSRLRIANA 295
            ..:.             |.|....|.|     |...||..   :|:|:      .:...|.|:..
Zfish   249 QAEA-------------YPGNLTYTWFWEEDNVFFKNDLK---RRVSI------LIDGSLIISQV 291

  Fly   296 QLLDTGNYTCMPTTA----EAASVVVNV 319
            :..|.|.|||.|:.:    .:||..:.|
Zfish   292 KPEDAGKYTCSPSNSLGRPPSASAYLTV 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	17/92 (18%)
		Ig	116..192	CDD:299845	15/75 (20%)
		ig	220..306	CDD:278476	19/90 (21%)
		IG_like	220..306	CDD:214653	19/90 (21%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	12/40 (30%)
		Ig	41..113	CDD:143165	12/40 (30%)
		IG_like	144..223	CDD:214653	17/93 (18%)
		IGc2	151..208	CDD:197706	15/71 (21%)
		I-set	227..319	CDD:254352	25/116 (22%)
		Ig	<263..319	CDD:299845	15/64 (23%)
		Ig_2	326..414	CDD:290606
		IG_like	329..403	CDD:214653
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910