DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr2 and cadm1b

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001107024.1	Gene:	cadm1b / 562183	ZFINID:	ZDB-GENE-080327-34	Length:	411	Species:	Danio rerio

Alignment Length:	191	Identity:	45/191 - (23%)
Similarity:	75/191 - (39%)	Gaps:	46/191 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 NITTRTGHTAAINCRVDNLGDKSVSWIRK-------RDLHILTAGILTYTSDERFKVVRTADSKD 172
            |::...|.||.|:|||.|..|..:..:..       ||:..|        .|.||::|..:|: :
Zfish    51 NVSVVEGETAIISCRVKNNDDSVIQLLNPNRQTIYFRDVRPL--------KDSRFQLVNFSDN-E 106

  Fly   173 WTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGPTDLYVKVGSSVTLTCHV 237
            ..:.:......|.|.|.||:.|:|.......:.|:|  |....|:....:: |..|:...:||
Zfish   107 LLVSLSNVSLSDEGRYVCQLYTDPPQEAYADITVLV--PPGNPILESREEI-VSEGNETEITC-- 166

  Fly   238 KQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAE------KLQSRLRI 292
              .|..::....|.|.:|.                 |.:..|:|:.|      .:.||||:
Zfish   167 --TAMGSKPASTIKWMKGD-----------------QPLQGEATVEELYDRMFTVTSRLRL 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	25/97 (26%)
		Ig	116..192	CDD:299845	21/82 (26%)
		ig	220..306	CDD:278476	16/79 (20%)
		IG_like	220..306	CDD:214653	16/79 (20%)
cadm1b	NP_001107024.1	Ig1_Necl-2	46..140	CDD:143289	25/97 (26%)
		IG_like	51..140	CDD:214653	25/97 (26%)
		Ig	161..242	CDD:299845	14/69 (20%)
		Ig_3	242..316	CDD:290638
		IG_like	252..329	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910