DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and sdk1a

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_009297968.1	Gene:	sdk1a / 558391	ZFINID:	ZDB-GENE-081104-374	Length:	2245	Species:	Danio rerio

Alignment Length:	263	Identity:	66/263 - (25%)
Similarity:	101/263 - (38%)	Gaps:	51/263 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 EAEEQPPEETTYPPPVFDFGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTY 156
            ||:.....:.|...|.|. ..|.:||...|..||..|||......::.|  :||..||.:|.:..
Zfish   496 EAQVHTYLDVTSMAPAFT-APPLDITVTDGAVAAFTCRVSGAPKPAIVW--RRDTQILASGSVQI 557

  Fly   157 TSDERFKVVRTADSKDWTLHVKYAQPRDSGIYEC-QVNTEPKISMAFRLNVIVTPPDAKAIIAGP 220
               .||.::.:..     |.::....:|:|.|.| ..|:|..|:.:..|.|.    ...:|.:.|
Zfish   558 ---PRFTLLESGG-----LQIQPVVLQDTGNYTCYAANSEGAINASASLTVW----SRTSISSPP 610

  Fly   221 TDLYVKVGSSVTLTCHVKQPATSAQDIGPIY-WYRGPYILTPFVAHPNDAAIDLQRISMESTLAE 284
            ||..|..|::..|.|    .||....:|..| |.:...:    |:|.....|.||
Zfish   611 TDRRVIKGTTAILEC----GATHDPRVGVRYVWKKDEEL----VSHSRGGRISLQ---------- 657

  Fly   285 KLQSRLRIANAQLLDTGNYTCMPTTAEAASVVVNVINDESPAAMQ------KSRAIRTSGSMRSS 343
              :..|.|:.....|.|||||        .|:....|:...|.::      ..|.::.|.:...|
Zfish   658 --EGSLHISQTWSGDIGNYTC--------DVISEAGNESKEARLEVIELPHSPRNLQASLNANDS 712

  Fly   344 RLV 346
            |.|
Zfish   713 RSV 715

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	26/93 (28%)
		Ig	116..192	CDD:299845	21/76 (28%)
		ig	220..306	CDD:278476	24/86 (28%)
		IG_like	220..306	CDD:214653	24/86 (28%)
sdk1a	XP_009297968.1	I-set	125..208	CDD:254352
		Ig	125..204	CDD:299845
		IG_like	222..302	CDD:214653
		Ig	236..287	CDD:299845
		Ig_3	322..394	CDD:290638
		I-set	323..412	CDD:254352
		I-set	416..505	CDD:254352	2/8 (25%)
		Ig	436..500	CDD:299845	2/3 (67%)
		I-set	510..600	CDD:254352	28/100 (28%)
		Ig	527..600	CDD:299845	22/82 (27%)
		I-set	605..693	CDD:254352	29/115 (25%)
		Ig	610..693	CDD:299845	28/110 (25%)
		FN3	697..788	CDD:238020	5/19 (26%)
		fn3	800..886	CDD:278470
		FN3	901..997	CDD:238020
		FN3	1002..1090	CDD:238020
		FN3	1100..1196	CDD:238020
		FN3	1206..1301	CDD:238020
		FN3	1308..1397	CDD:238020
		FN3	1408..1501	CDD:238020
		FN3	1507..1602	CDD:238020
		FN3	1616..1722	CDD:238020
		FN3	1732..1825	CDD:238020
		FN3	1830..1919	CDD:238020
		FN3	1931..2021	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910