DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and ptk7a

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001018501.1	Gene:	ptk7a / 553690	ZFINID:	ZDB-GENE-050522-216	Length:	231	Species:	Danio rerio

Alignment Length:	196	Identity:	38/196 - (19%)
Similarity:	75/196 - (38%)	Gaps:	48/196 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 ISRAWTMQQQHLSPAIQQHPAVKSLSHLVDGNDNLLPMVSAPSSIDN-DYVYIASVNRKFPQFGN 85
            :|.||....:         |...|....:||.:  |...:...::|: ::..|||.|
Zfish    65 VSYAWIQNGE---------PVTNSERRFLDGGN--LKFTAIDRTLDSGNFQCIASKN-------- 110

  Fly    86 SIDDEREAEEQPPEETTYPPPVFDFG-----MPRNIT-TRTGHTAAINCRVDNLGDKSVSWIRKR 144
                 ...||:...||::.....:.|     .|.::. .::.....:.|.:|.....:..|.:..
Zfish   111 -----STGEEERTAETSFNIKWLESGAVSLKSPESVAEIQSSSQVILRCNIDGHPRPTNRWFKDG 170

  Fly   145 DLHILTAGILTYTSDERFKVVRTADSKDWTLHVKYAQPRDSGIYE-CQVNTEPKI--SMAFRLNV 206
                      |..:::.:|:    ::|:.:|.:..|.|.|:|:|. |..|...::  |..|.||:
Zfish   171 ----------TQITEKNYKI----NNKERSLTLPNASPDDNGLYFCCAKNAAGQVCSSDNFTLNI 221

  Fly   207 I 207
            |
Zfish   222 I 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	18/96 (19%)
		Ig	116..192	CDD:299845	13/77 (17%)
		ig	220..306	CDD:278476
		IG_like	220..306	CDD:214653
ptk7a	NP_001018501.1	I-set	37..120	CDD:254352	15/78 (19%)
		Ig	42..122	CDD:299845	16/80 (20%)
		Ig	150..222	CDD:299845	18/85 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910