DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr2 and Ntm

DIOPT Version :9

Sequence 1:NP_001014480.4 Gene:dpr2 / 3346227 FlyBaseID:FBgn0261871 Length:410 Species:Drosophila melanogaster
Sequence 2:XP_017451354.1 Gene:Ntm / 50864 RGDID:620958 Length:367 Species:Rattus norvegicus


Alignment Length:277 Identity:59/277 - (21%)
Similarity:117/277 - (42%) Gaps:59/277 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   100 ETTYPPPVFDFGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFKV 164
            :.|:|..:      .|:|.|.|.:|.:.|.:||...: |:|:.:..  ||.||...:..|.|..:
  Rat    35 DATFPKAM------DNVTVRQGESATLRCTIDNRVTR-VAWLNRST--ILYAGNDKWCLDPRVVL 90

  Fly   165 VRTADSKDWTLHVKYAQPRDSGIYECQVNTE--PKISMAFRLNVIVTPPDAKAIIAGPTDLYVKV 227
            :....:: :::.::.....|.|.|.|.|.|:  ||.|   |:::||..  :..|:...:|:.:..
  Rat    91 LSNTQTQ-YSIEIQNVDVYDEGPYTCSVQTDNHPKTS---RVHLIVQV--SPKIVEISSDISINE 149

  Fly   228 GSSVTLTCHV---KQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAEKLQSR 289
            |::::|||..   .:|..:.:.|.|        ....||:  .|..:::|.|:.|          
  Rat   150 GNNISLTCIATGRPEPTVTWRHISP--------KAVGFVS--EDEYLEIQGITRE---------- 194

  Fly   290 LRIANAQLLDTGNYTCMPTTAEAASVVVNV-INDESPAAMQKSRA----IRTSGSMRSSRLVLLL 349
                     .:|.|.|..:...||.||..| :....|..:.:::.    :...|:::..     .
  Rat   195 ---------QSGEYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCE-----A 245

  Fly   350 AMVASSVVRWLIGGQRI 366
            :.|.|:..:|....:|:
  Rat   246 SAVPSAEFQWFKDDKRL 262

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr2NP_001014480.4 IG_like 113..206 CDD:214653 26/94 (28%)
Ig 116..192 CDD:299845 19/75 (25%)
ig 220..306 CDD:278476 16/88 (18%)
IG_like 220..306 CDD:214653 16/88 (18%)
NtmXP_017451354.1 Ig 44..132 CDD:416386 26/94 (28%)
Ig strand A' 44..49 CDD:409353 2/4 (50%)
Ig strand B 51..59 CDD:409353 2/7 (29%)
CDR1 59..63 CDD:409353 2/3 (67%)
FR2 64..70 CDD:409353 2/6 (33%)
Ig strand C 64..70 CDD:409353 2/6 (33%)
CDR2 71..83 CDD:409353 4/13 (31%)
Ig strand C' 72..76 CDD:409353 1/5 (20%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 6/34 (18%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/6 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 4/11 (36%)
FR4 125..132 CDD:409353 2/9 (22%)
Ig_3 136..205 CDD:404760 18/97 (19%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand F 197..205 CDD:409353 3/7 (43%)
Ig 223..307 CDD:416386 5/45 (11%)
putative Ig strand A 223..229 CDD:409353 0/5 (0%)
Ig strand B 239..243 CDD:409353 1/3 (33%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353
Ig strand F 292..297 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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