DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and dpr10

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster

Alignment Length:	400	Identity:	125/400 - (31%)
Similarity:	186/400 - (46%)	Gaps:	107/400 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 SIDDEREAEEQPPEETTYPP-----------PVFDFGMPRNITTRTGHTAAINCRVDNLGDKSVS 139
            |.::...||.:|   |..||           |.||..||||||:..|.:|.:.|||.:||:|:|:
  Fly    25 SNNNHNNAEAKP---THAPPSHYPHGHKWNEPYFDLTMPRNITSLVGKSAYLGCRVKHLGNKTVA 86

  Fly   140 WIRKRDLHILTAGILTYTSDERFKVVRTADSKDWTLHVKYAQPRDSGIYECQVNTEPKISMAFRL 204
            |||.|||||||.|..|||:|:||:.....|..:|||.:|:||.||:|:||||::|:|..|.:..|
  Fly    87 WIRHRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIKWAQQRDAGVYECQISTQPVRSYSVNL 151

  Fly   205 NVI--------------------------------------------VTPPDAKAIIAGPTDLYV 225
            |::                                            |..|.| .|:.|| ||||
  Fly   152 NIVDLIDAETSDIMQQYYNDDAFYIAENRVYQSSNDEFAGMFGPIQTVAVPTA-TILGGP-DLYV 214

  Fly   226 KVGSSVTLTCHVK---QPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAEKLQ 287
            ..||::.|||.:|   :|.|.      |:||....:|:...:.        .|:..::..:|:.:
  Fly   215 DKGSTINLTCIIKFSPEPPTH------IFWYHQDKVLSEETSG--------GRLKFKTIKSEETK 265

  Fly   288 SRLRIANAQLLDTGNYTCMPTTAEAASVVVNVINDESPAAM-------------------QKSRA 333
            |.|.|.:|.||.:|.|:|.|:..|.||:.|:|:..|.|.||                   |.::|
  Fly   266 SILLIYDADLLHSGKYSCYPSNTEIASIRVHVLQGERPEAMQTNAAPAAVALACWSCHFGQATQA 330

  Fly   334 IRTSGSMRSSRLVLLLAMVASSVVRWLIGGQRIGSNSCHDSCSNLSTLHINYCNLRAK-ITSHLK 397
            :|...:|.:: ||||.|  .||::.     |..|...|....|....:......:|.| :|:.|.
  Fly   331 VRVISTMVAA-LVLLEA--CSSLLL-----QSGGGGGCPGGGSPAGGMPTRVREIREKPLTNSLL 387

  Fly   398 EHRCLGPGST 407
            :.:.  |.:|
  Fly   388 DPKI--PSTT 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	49/92 (53%)
		Ig	116..192	CDD:299845	41/75 (55%)
		ig	220..306	CDD:278476	27/88 (31%)
		IG_like	220..306	CDD:214653	27/88 (31%)
dpr10	NP_729591.1	Ig	63..143	CDD:299845	43/79 (54%)
		IG_like	210..297	CDD:214653	33/101 (33%)
		IGc2	217..287	CDD:197706	24/83 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444672
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I3769
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.990