DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and dscamb

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_009289749.1	Gene:	dscamb / 386937	ZFINID:	ZDB-GENE-031118-67	Length:	2020	Species:	Danio rerio

Alignment Length:	309	Identity:	64/309 - (20%)
Similarity:	116/309 - (37%)	Gaps:	70/309 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 TPILVIMISISRAWTMQQQHLSPAIQQHPAVKSLSHLVD----GNDNLLPMVS-APSSIDNDYVY 72
            ||:..:      .||:...         |.:|..:|.:|    ...::|..:: :.:.:.:..||
Zfish   433 TPLPTV------TWTLDDD---------PVIKDSNHRMDRIITTEGHVLSYLNVSHTQVSDGGVY 482

  Fly    73 IASVNRKFPQFGNSIDDEREAEEQPPEETTYPPPVFDFGMPRNITTRTGHTAAINCRVDNLGDKS 137
            ..:.|..    ..|:..:.....:.|....   |:      :|:|...|....|:||:......|
Zfish   483 RCTCNNS----AGSVSYQARINVRGPASIR---PM------KNVTAIAGRDTYIHCRIIGYPYYS 534

  Fly   138 VSWIRKRDLHILTAGILTYTSDERFKVVRTADSKDWTLHVKYAQPRDSGIYECQVNTEPKISMAF 202
            :.|.:..:|       |.:...:|      |...:.||.:...|..|.|.|.|.|..:|:..:..
Zfish   535 IKWYKDSNL-------LPFNHRQR------AFENNGTLKLSNVQNSDEGEYTCYVLVDPEKQIHR 586

  Fly   203 RLNVIV-TPPDAKAIIAGPTDLYVKVGSSVTLTCHVKQPATSAQDIGPIYWYRGPYILTPFVAHP 266
            .::|.| .||    :|.........:|..|.:.|.|    .|......|.|::.        ..|
Zfish   587 SVHVTVKVPP----LIQHSDSQSASIGQRVFIPCVV----ISGDLPMSITWHKD--------GRP 635

  Fly   267 NDAAIDLQRISMESTLAEKLQSRLRIANAQLLDTGNYTCMPTTAEAASV 315
            .:|::.:...:::.|      |.|||:|...:..|:|||:... |||:|
Zfish   636 INASLGVTIDNIDFT------SSLRISNLSEIHNGSYTCIARN-EAAAV 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	21/92 (23%)
		Ig	116..192	CDD:299845	18/75 (24%)
		ig	220..306	CDD:278476	18/85 (21%)
		IG_like	220..306	CDD:214653	18/85 (21%)
dscamb	XP_009289749.1	I-set	132..198	CDD:254352
		I-set	225..310	CDD:254352
		IGc2	239..300	CDD:197706
		IG_like	320..400	CDD:214653
		IGc2	328..391	CDD:197706
		IG_like	417..501	CDD:214653	13/86 (15%)
		Ig	424..498	CDD:143165	13/83 (16%)
		IG_like	511..592	CDD:214653	22/93 (24%)
		IGc2	518..576	CDD:197706	17/70 (24%)
		I-set	595..685	CDD:254352	26/106 (25%)
		Ig	612..682	CDD:143165	22/85 (26%)
		I-set	689..785	CDD:254352
		Ig7_DSCAM	706..785	CDD:143211
		IG_like	795..883	CDD:214653
		Ig	803..890	CDD:299845
		FN3	887..980	CDD:238020
		FN3	987..1084	CDD:238020
		FN3	1092..1185	CDD:238020
		FN3	1190..1279	CDD:238020
		IGc2	1302..1367	CDD:197706
		FN3	1398..1471	CDD:238020
		FN3	1485..1557	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910