DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and Gm1123

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001074245.1	Gene:	Gm1123 / 382097	MGIID:	2685969	Length:	390	Species:	Mus musculus

Alignment Length:	267	Identity:	61/267 - (22%)
Similarity:	104/267 - (38%)	Gaps:	69/267 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 YIASVNRKFPQFGNSIDDEREAEEQPPEETTYPPPVFDFGMPRNITTRTGHTAAINCRVDNLGDK 136
            ||.||         ||....:..|:...||.:.|.:|.|               |:   .:.|..
Mouse   141 YIGSV---------SITTPEQTIEKDQGETVHLPCMFTF---------------IS---KDQGPL 178

  Fly   137 SVSWIR-------KRDLHILTAGILTYTSDE---------RFKVVRTAD---SKDWTLHVKYAQP 182
            ::.|:|       ..| |:    ::.|::|:         :.:|..|::   |.|.::::...|.
Mouse   179 NIEWLRLSGPNNEAMD-HV----VILYSADKIHDDVYPDLKGRVYFTSNDIKSGDASINITNVQL 238

  Fly   183 RDSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGPTDLYVKV-GSSVTLTCHVKQPATSAQD 246
            .|:|.|:|:|.|.|. ::...|.:.||.......|..|.....|. |.:|.|.|..   ..|.:|
Mouse   239 SDAGTYQCKVKTYPG-TVNRNLQLAVTDHIGSVSITTPEQTIQKARGETVHLPCTF---TLSPED 299

  Fly   247 IGPIY--WYR--GP---YILTPFVAHPNDAAID------LQRISMESTLAEKLQSRLRIANAQLL 298
            .||::  |.:  ||   .:...|:.:..|...|      ..|:...|......::.:.|.:|:|.
Mouse   300 HGPLFIDWMQLTGPQNEVVNRMFIVYLADKIYDNFYQDMKGRVQFTSNDIRSGEASINITDARLS 364

  Fly   299 DTGNYTC 305
            |.|.|.|
Mouse   365 DAGTYQC 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	21/111 (19%)
		Ig	116..192	CDD:299845	17/94 (18%)
		ig	220..306	CDD:278476	25/100 (25%)
		IG_like	220..306	CDD:214653	25/100 (25%)
Gm1123	NP_001074245.1	V-set	24..139	CDD:284989
		IG_like	25..138	CDD:214653
		V-set	149..264	CDD:284989	27/138 (20%)
		IG_like	152..263	CDD:214653	27/134 (20%)
		V-set	274..389	CDD:284989	25/101 (25%)
		IG_like	277..388	CDD:214653	24/98 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910