DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and dpr20

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_612066.1	Gene:	dpr20 / 38101	FlyBaseID:	FBgn0035170	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	92/362 - (25%)
Similarity:	156/362 - (43%)	Gaps:	74/362 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IATPILVIMISISRAWTMQQQHLSPAIQQHPAVK--SLSHLVDGNDNLLPMVSAPSSIDNDYVYI 73
            :|||            |...::.|..:.::.|||  |...|..|.....||:        :|::
  Fly   204 LATP------------TEPARNRSTGLVRNSAVKVDSKHPLSKGQKTDAPML--------NYIF- 247

  Fly    74 ASVNRKFPQFGNSIDDEREAEEQPPEETTYPPPVFD---FGMPRNITTRTGHTAAINCRVDNLGD 135
                          |....|.:....:..|.|...|   .|...|:|.:.|.:..:|||:..|.|
  Fly   248 --------------DTFSSANKHHHHDQRYGPHFEDVQRIGQATNLTVQAGSSIHLNCRISLLQD 298

  Fly   136 KSVSWIRKRD----------LHILTAGILTYTSDERFKVVRTADSKDWTLHVKYAQPRDSGIYEC 190
            |:|||:|...          |.:||.|:.|||.|:|:| :......:|.|.:...:..|..||||
  Fly   299 KTVSWVRHNTQDEGKDNGNALDLLTVGMHTYTGDKRYK-MEFQYPNNWRLKITNVKKDDEAIYEC 362

  Fly   191 QVNTEPKISMAFRLNVIVTPPDAKAI--IAGP-TDLYVKVGSSVTLTCHVKQPATSAQDIGPIYW 252
            |::|.|  ....::|:.|..|....:  :..| .:.|.::.|::.|:|.|:..|.::   ..::|
  Fly   363 QISTHP--PRVIQINLHVNAPKVMIVDEVGDPLQEKYYEIDSTLQLSCVVRNVAMTS---SVVFW 422

  Fly   253 YRGPYILTPFVAHPNDAAIDLQR--ISMESTLAEK-LQSRLRIANAQLLDTGNYTCMPTTAEAAS 314
            .....||.          .|:.|  :|:::.|.|. ..|.|.||.....|:|||||..:..:..:
  Fly   423 KHMDNILN----------YDVTRGGVSVKTELMEDGANSTLSIAKISKTDSGNYTCSISEFQNFT 477

  Fly   315 VVVNVINDESPAAMQKSRAIRTSGSMRSSRLVLLLAM 351
            :||:::|.||.|.:....|:....:..:  :|:|.||
  Fly   478 IVVHILNGESFAELHHGGAVGWHSTWWN--MVMLHAM 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	33/102 (32%)
		Ig	116..192	CDD:299845	29/85 (34%)
		ig	220..306	CDD:278476	24/89 (27%)
		IG_like	220..306	CDD:214653	24/89 (27%)
dpr20	NP_612066.1	IG_like	278..365	CDD:214653	31/87 (36%)
		Ig	279..378	CDD:299845	33/101 (33%)
		Ig	400..471	CDD:299845	23/83 (28%)
		IG_like	402..480	CDD:214653	23/90 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444715
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.940