DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr2 and Cadm4

DIOPT Version :9

Sequence 1:NP_001014480.4 Gene:dpr2 / 3346227 FlyBaseID:FBgn0261871 Length:410 Species:Drosophila melanogaster
Sequence 2:NP_001040572.1 Gene:Cadm4 / 365216 RGDID:1304722 Length:388 Species:Rattus norvegicus


Alignment Length:283 Identity:65/283 - (22%)
Similarity:103/283 - (36%) Gaps:79/283 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   115 NITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFKV---------VRTADS 170
            |:|...|..|.|.||:... |.|:..|:......|.........||||::         :|.:| 
  Rat    31 NVTVAEGGVAEITCRLHQY-DGSIVVIQNPARQTLFFNGTRALKDERFQLEEFSPRRVRIRLSD- 93

  Fly   171 KDWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGPTDLYVKV------GS 229
                     |:..|.|.|.||:.||........|.|:|.|.:.          .|:|      |.
  Rat    94 ---------ARLEDEGGYFCQLYTEDTHHQIATLTV
LVAPENP----------VVEVREQAVEGG 139

  Fly   230 SVTLTCHVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAEKLQSRLRI-- 292
            .|.|:|.|.:...:|    .:.|||....|....:...:..:    .|:.||:      |.|:  
  Rat   140 EVELSCLVPRSRPAA----VLRWYRDRKELKGVSSGQENGKV----WSVASTV------RFRVDR 190

  Fly   293 ----------ANAQLLDTGNYTCMPTTAEAASVVVNVINDESPAA-MQKSRAIRTSGSMRSSRLV 346
                      |..|.|.:|:       ::....|::|  ..||.| :..|:|:...|    ..||
  Rat   191 KDDGGIVICEAQNQALPSGH-------SKQTQYVLDV--QYSPTARIHASQAVVREG----DTLV 242

  Fly   347 LLLAMVAS---SVVRWLIGGQRI 366
            |..|:..:   :.:||..|.:.:
  Rat   243 LTCAVTGNPRPNQIRWNRGNESL 265

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr2NP_001014480.4 IG_like 113..206 CDD:214653 26/99 (26%)
Ig 116..192 CDD:299845 21/84 (25%)
ig 220..306 CDD:278476 21/103 (20%)
IG_like 220..306 CDD:214653 21/103 (20%)
Cadm4NP_001040572.1 Ig 29..120 CDD:416386 26/99 (26%)
FR1 29..45 CDD:409353 5/13 (38%)
Ig strand A' 30..36 CDD:409353 2/4 (50%)
Ig strand B 38..46 CDD:409353 3/7 (43%)
CDR1 46..51 CDD:409353 0/5 (0%)
FR2 52..59 CDD:409353 2/6 (33%)
Ig strand C 52..58 CDD:409353 2/5 (40%)
CDR2 60..71 CDD:409353 1/10 (10%)
Ig strand C' 62..66 CDD:409353 1/3 (33%)
Ig strand C' 68..71 CDD:409353 0/2 (0%)
FR3 72..107 CDD:409353 12/44 (27%)
Ig strand D 76..83 CDD:409353 2/6 (33%)
Ig strand E 86..92 CDD:409353 1/5 (20%)
Ig strand F 99..107 CDD:409353 4/7 (57%)
CDR3 108..111 CDD:409353 2/2 (100%)
Ig strand G 111..120 CDD:409353 1/8 (13%)
FR4 113..120 CDD:409353 1/6 (17%)
IgI_2_Necl-4 121..220 CDD:409468 24/129 (19%)
Ig strand B 141..145 CDD:409468 2/3 (67%)
Ig strand C 155..159 CDD:409468 0/3 (0%)
Ig strand E 182..186 CDD:409468 2/9 (22%)
Ig strand F 196..201 CDD:409468 0/4 (0%)
Ig strand G 213..216 CDD:409468 0/2 (0%)
Ig strand A' 231..235 CDD:409353 2/3 (67%)
IGc2 237..298 CDD:197706 8/33 (24%)
Ig strand B 241..248 CDD:409353 4/6 (67%)
Ig strand C 255..260 CDD:409353 2/4 (50%)
Ig strand C' 262..264 CDD:409353 0/1 (0%)
Ig strand E 274..280 CDD:409353
Ig strand F 287..294 CDD:409353
Ig strand G 300..308 CDD:409353
4.1m 344..362 CDD:128590
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 41 1.000 Domainoid score I12165
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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