DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and DIP-theta

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	86/338 - (25%)
Similarity:	129/338 - (38%)	Gaps:	89/338 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ATPILVIMISISRAW------------------TMQQQHLSPAI---QQHPAVKSLSHLVD--GN 53
            ||..:|.:|.:|.|.                  .|..||....|   ::|..:  ..||.:  ..
  Fly    46 ATAAVVSIICLSLALPGCAAQESDDEGELHHLDQMHHQHQDFIIGESEEHDHI--AHHLAEMQNK 108

  Fly    54 DNLLPMVSAPSSIDNDYVYIASVNRKFPQFGNSIDDEREAEEQPPEETTYPPPVFDFGMPRNITT 118
            |.||      ..|..|.|..|...:..|:||..:                          :|:|.
  Fly   109 DELL------EDIREDTVVNAIPEKDLPKFGELL--------------------------QNVTV 141

  Fly   119 RTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFKVVRTADSKDWTLHVKYAQPR 183
            .....|.:.|.||||....::|:|.....|||......|.:.|..:.. |:.:.|.|.::..:..
  Fly   142 PVSREAVLQCVVDNLQTYKIAWLRVDTQTILTIQNHVITKNHRMSITH-AEKRAWILRIRDVKES 205

  Fly   184 DSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGP--TDLYVKVGSSVTLTCHVKQPATSAQD 246
            |.|.|.||:||:|..|....|:|:| |||   |:..|  ||:.::.||:|||.|     |.:...
  Fly   206 DKGWYMCQINTDPMKSQVGYLDVVV-PPD---ILDYPTSTDMVIREGSNVTLKC-----AATGSP 261

  Fly   247 IGPIYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAEKLQSRLRIANAQLLDTGNYTCM----- 306
            ...|.|.|....|.|.   ||.|    :.::...       |.|.||....|:.|.|.|:
  Fly   262 TPTITWRREGGELIPL---PNGA----EAVAYNG-------SFLTIAKVNRLNMGAYLCIASNGI 312

  Fly   307 -PTTAEAASVVVN 318
             ||.::...::|:
  Fly   313 PPTVSKRVMLIVH 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	28/92 (30%)
		Ig	116..192	CDD:299845	21/75 (28%)
		ig	220..306	CDD:278476	25/87 (29%)
		IG_like	220..306	CDD:214653	25/87 (29%)
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	29/93 (31%)
		IG_like	137..230	CDD:214653	29/93 (31%)
		IG_like	240..324	CDD:214653	27/102 (26%)
		IGc2	247..310	CDD:197706	23/81 (28%)
		Ig	327..419	CDD:299845
		IG_like	343..420	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910