DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr2 and Jaml

DIOPT Version :9

Sequence 1:NP_001014480.4 Gene:dpr2 / 3346227 FlyBaseID:FBgn0261871 Length:410 Species:Drosophila melanogaster
Sequence 2:XP_038938277.1 Gene:Jaml / 315610 RGDID:1562572 Length:379 Species:Rattus norvegicus


Alignment Length:313 Identity:64/313 - (20%)
Similarity:117/313 - (37%) Gaps:89/313 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   104 PPPVFDFGMPRNITTRT----------GHTAAINCRVDNLGDK---SVSWIRKRDLHILTAGILT 155
            |..:...|.|:.:...|          |.:|.:.|.|.:..:|   .|.|:..:..|.....:|.
  Rat    11 PVVLVSVGYPQGLPDLTVSSLKLRVHVGESALMGCVVQSTEEKPVDKVDWVFSKGEHAENEYVLY 75

  Fly   156 YTS---------DERFKVVRTADSKDWTLHVKYAQPRDSGIYECQV--NTEPKISMAFRLNVIVT 209
            |.|         ..|.::|......|.:|.::..|..|.|||.|::  ..|..:|..|.| :.|.
  Rat    76 YYSSLSVPTGRFQNRSRLVGDLLRNDGSLLLQDVQKADEGIYTCEIRLKNEGSVSKKFVL-LHVL 139

  Fly   210 PPDAKAIIAGPTDLYVKVGSSVTLTCHVKQPATSAQDIGPIYW---------------------- 252
            |.:       |.:|.|.||..:.:.|..:  :|..:.:..:.|                      
  Rat   140 PEE-------PKELRVHVGDPIQMGCFFR--STEERRVTRVNWMFSSGKHAQEEIVLSYDFNMHS 195

  Fly   253 --------YRGPYILTPFVAHPNDAAIDLQRISMESTLAEKLQSRLRIANAQLLDTGNYTC---M 306
                    :|....||..::. ||.:|.||.:...                   |.|.|||   :
  Rat   196 GTFQGQGRFRNRVDLTGDISR-NDGSIMLQTVKKS-------------------DQGVYTCSIYL 240

  Fly   307 PTTAEAASVVVNVINDESPAAMQKS--RAIRTSGSMRSSRLVLLLAMVASSVV 357
            .......::|::||.||||.::..:  .|.:..|.:..::||:::.:|.::::
  Rat   241 GKLESRKTIVLHVIQDESPRSISTTTETAGKQQGILDGNQLVIIVGIVCATLL 293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr2NP_001014480.4 IG_like 113..206 CDD:214653 27/116 (23%)
Ig 116..192 CDD:299845 22/97 (23%)
ig 220..306 CDD:278476 21/118 (18%)
IG_like 220..306 CDD:214653 21/118 (18%)
JamlXP_038938277.1 V-set 33..139 CDD:400157 25/106 (24%)
FR2 58..69 CDD:409353 3/10 (30%)
CDR2 70..82 CDD:409353 3/11 (27%)
Ig strand C' 71..77 CDD:409353 1/5 (20%)
Ig strand C' 78..82 CDD:409353 1/3 (33%)
FR3 87..121 CDD:409353 10/33 (30%)
Ig strand D 90..96 CDD:409353 2/5 (40%)
Ig strand E 100..108 CDD:409353 2/7 (29%)
Ig strand F 115..122 CDD:409353 4/6 (67%)
V-set 141..253 CDD:400157 22/140 (16%)
Ig strand A' 144..150 CDD:409353 2/5 (40%)
Ig strand B 152..162 CDD:409353 1/11 (9%)
CDR1 162..169 CDD:409353 1/6 (17%)
Ig strand C 169..176 CDD:409353 1/6 (17%)
FR2 170..181 CDD:409353 1/10 (10%)
CDR2 182..196 CDD:409353 0/13 (0%)
Ig strand C' 183..189 CDD:409353 0/5 (0%)
Ig strand C' 191..196 CDD:409353 0/4 (0%)
FR3 204..238 CDD:409353 13/53 (25%)
Ig strand D 207..213 CDD:409353 2/5 (40%)
Ig strand E 217..225 CDD:409353 4/7 (57%)
Ig strand F 232..238 CDD:409353 4/5 (80%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 48 1.000 Inparanoid score I5388
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.960

Return to query results.
Submit another query.