DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and dpr9

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001287332.1	Gene:	dpr9 / 2768670	FlyBaseID:	FBgn0038282	Length:	602	Species:	Drosophila melanogaster

Alignment Length:	349	Identity:	117/349 - (33%)
Similarity:	169/349 - (48%)	Gaps:	69/349 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 NSIDDEREAEEQPPEETTYPPPVFDFGMPRNITTRTGHTAAINCRVDNLGDKS----VSWIRKRD 145
            ||||         .||.....|.||....:|:|...|.||.:||||.|||:|:    |||:|.||
  Fly   244 NSID---------LEEARNAGPYFDKAFSKNVTALLGKTAYLNCRVKNLGNKTMLLQVSWVRHRD 299

  Fly   146 LHILTAGILTYTSDERFKVVRTADSKDWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTP 210
            :|:||.|..|||||:||:.:....::||.|.:||.|.||||||||||:|.|.:|....|||:
  Fly   300 IHLLTVGRYTYTSDQRFRAIHQPQTEDWMLQIKYPQHRDSGIYECQVSTTPHMSHYIHLNVV--- 361

  Fly   211 PDAKAIIAGPTDLYVKVGSSVTLTCHVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQR 275
             :....|.|..|||::.||::.|||.::   .|.:....|:|...    ..|.:||.....|..|
  Fly   362 -EPSTEIIGAPDLYIESGSTINLTCIIQ---NSPEPPAYIFWNHN----NAFPSHPQIINYDSPR 418

  Fly   276 --ISMESTLAEKLQSRLRIANAQLLDTGNYTCMPTTAEAASVVVNVINDESPAAMQKSRAIRTS- 337
              :|:.:...:...|.|.|.:|:..|:|:|.|.|:.|:..||.|:|:|..|.:.   ||.:.:|
  Fly   419 GGVSVVTNKGDTTTSFLLIKSARPSDSGHYQCNPSNAKPKSVTVHVLNGVSHSV---SRGVPSSN 480

  Fly   338 ---GSMRSSRL-------VLLLAMVASSVVRW---LIG----------------GQRIGSNSCHD 373
               |:..||.|       |.:..::.....||   |:|                |:|.||..|..
  Fly   481 AARGTSASSPLAHSLSVCVPVCVLLQLGACRWIAALLGAALATPPPLRSTRRATGERPGSPGCAP 545

  Fly   374 SCSNLSTLHINYCNLRAKITSHLK 397
            ..          |::|..:.|.|:
  Fly   546 IA----------CDMRHFLASVLR 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	50/96 (52%)
		Ig	116..192	CDD:299845	43/79 (54%)
		ig	220..306	CDD:278476	24/87 (28%)
		IG_like	220..306	CDD:214653	24/87 (28%)
dpr9	NP_001287332.1	Ig	263..361	CDD:299845	51/97 (53%)
		IG_like	263..360	CDD:214653	50/96 (52%)
		IG_like	371..464	CDD:214653	30/99 (30%)
		IGc2	377..456	CDD:197706	23/85 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444729
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I5030
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X190
	7	6.990