DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and Tyro3

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_058788.1	Gene:	Tyro3 / 25232	RGDID:	3923	Length:	880	Species:	Rattus norvegicus

Alignment Length:	327	Identity:	67/327 - (20%)
Similarity:	117/327 - (35%)	Gaps:	100/327 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 GMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFKVVRTADSKDW-- 173
            |.|..:|...|....:||.|:.:.|..:.|::.        |.:...:.:   |..:...::|
  Rat    37 GAPVKMTVSQGQPVKLNCSVEGMDDPDIHWMKD--------GAVVQNASQ---VSISISEQNWIG 90

  Fly   174 TLHVKYAQPRDSGIYECQV--NTEPKISMAFRLNVIVTPPDAKAIIAGPTDLYVKVGSSVTLTCH 236
            .|.:|.|:..|:|:|.|||  ..|.|||.:..|.|...|    .....|.||.|.......|:|
  Rat    91 LLSLKSAERSDAGLYWCQVKDGEETKISQSVWLTVEGVP----FFTVEPKDLAVPPNVPFQLSC- 150

  Fly   237 VKQPATSAQDIGP-----IYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAEKLQSRLRIANAQ 296
                    :.:||     |:|:|||..:....:.|  :.:::..::..:..:
  Rat   151 --------EAVGPPEPVTIFWWRGPTKVGGPASSP--SVLNVTGVTQRTEFS------------- 192

  Fly   297 LLDTGNYTCMPTTAEAASVVVNVINDESPAAMQKSRAIRTSGSMRSSRLVLLLAMVASSVVRWLI 361
             .:..|...:.|:..|      :|..::|.|...:..:.|..|..:|             |.|:.
  Rat   193 -CEAHNIKGLATSRPA------IIRLQAPPAAPFNITVTTISSSNAS-------------VAWVP 237

  Fly   362 GGQRIG-SNSCHDSCSNLSTLHINY------------------CNLR--AKITSHLKEHRC---L 402
            |...:. .:||        |:.:.:                  |.||  |..|::....||   |
  Rat   238 GADGLALLHSC--------TVQVAHAPGEWEALAVVVPVPPFTCLLRNLAPATNYSLRVRCANAL 294

  Fly   403 GP 404
            ||
  Rat   295 GP 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	25/96 (26%)
		Ig	116..192	CDD:299845	17/77 (22%)
		ig	220..306	CDD:278476	15/90 (17%)
		IG_like	220..306	CDD:214653	15/90 (17%)
Tyro3	NP_058788.1	IG_like	39..125	CDD:214653	25/96 (26%)
		IGc2	46..111	CDD:197706	18/75 (24%)
		Ig2_Tyro3_like	131..209	CDD:143226	17/108 (16%)
		IG_like	135..204	CDD:214653	15/93 (16%)
		FN3	215..307	CDD:238020	20/103 (19%)
		fn3	315..396	CDD:278470
		PTKc_Tyro3	498..781	CDD:270659
		Pkinase_Tyr	508..776	CDD:285015
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	804..827
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	842..864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910