DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr2 and IGSF9B

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_001264214.1	Gene:	IGSF9B / 22997	HGNCID:	32326	Length:	1437	Species:	Homo sapiens

Alignment Length:	263	Identity:	59/263 - (22%)
Similarity:	82/263 - (31%)	Gaps:	95/263 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 PVFDFGMPRNITTRTGHTAAINCRVDNL-GDKSVSWIRKRDLHILTAGILTYTSDERFKVVRTAD 169
            |.|....|.|||......|.:.||.:.. |:.:.:|               |..||  .|....|
Human   228 PPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTW---------------YWQDE--NVYFQND 275

  Fly   170 SK-------DWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAKA---------IIA 218
            .|       |.||.:...:|.|||.|.|..:           |.:...|.|.|         ::.
Human   276 LKLRVRILIDGTLIIFRVKPEDSGKYTCVPS-----------NSLGRSPSASAYLTVQYPARVLN 329

  Fly   219 GPTDLYVKVGSSVTLTCHV--KQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMEST 281
            .|..:||.||....:.|.|  :.|||      .:.|.:                 |.:.:.:|..
Human   330 MPPVIYVPVGIHGYIRCPVDAEPPAT------VVKWNK-----------------DGRPLQVEKN 371

  Fly   282 LAEKL--QSRLRIANAQLLDTGNYTCMPTTAEAASVVVNVINDESPAAMQKSRAIRTSGSMRSSR 344
            |...|  ...:||..|.....|.|||:|                       ...:.|.|....:|
Human   372 LGWTLMEDGSIRIEEATEEALGTYTCVP-----------------------YNTLGTMGQSAPAR 413

  Fly   345 LVL 347
            |||
Human   414 LVL 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	24/100 (24%)
		Ig	116..192	CDD:299845	22/83 (27%)
		ig	220..306	CDD:278476	21/89 (24%)
		IG_like	220..306	CDD:214653	21/89 (24%)
IGSF9B	NP_001264214.1	IG_like	30..115	CDD:214653
		Ig	41..115	CDD:143165
		I-set	139..225	CDD:254352
		IGc2	153..210	CDD:197706
		I-set	229..321	CDD:254352	29/119 (24%)
		Ig	235..321	CDD:299845	28/113 (25%)
		IG_like	331..414	CDD:214653	25/128 (20%)
		Ig	<353..414	CDD:299845	18/106 (17%)
		IG_like	426..505	CDD:214653
		Ig	442..505	CDD:299845
		FN3	510..601	CDD:238020
		FN3	617..699	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	758..817
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	911..1081
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910