DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and AgaP_AGAP004915

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_315006.4	Gene:	AgaP_AGAP004915 / 1275796	VectorBaseID:	AGAP004915	Length:	458	Species:	Anopheles gambiae

Alignment Length:	236	Identity:	64/236 - (27%)
Similarity:	97/236 - (41%)	Gaps:	51/236 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 EETTYPPPVFDFGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFK 163
            :|..:..|:      .|:|...|..|.:.|.|::||...|:||     ||....|||.......:
Mosquito    42 DEPRFAQPI------PNVTVAVGRDANLPCVVEHLGTYKVAWI-----HIDRQMILTIHRHVISR 95

  Fly   164 VVRTA----DSKDWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGPTDLY 224
            :.|.:    :|..|.|||..||..|.|.|.|||||.|.||....|.|:| ||:...|.:.|:.:.
Mosquito    96 IPRYSVTYDNSNTWLLHVSQAQQDDRGYYMCQVNTNPMISQVGYLQVVV-PPNILDIESTPSSVA 159

  Fly   225 VKVGSSVTLTCHVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAEKLQSR 289
            |:...::.:||......|.     .|.|.|.                |.|.|::|.      :.:
Mosquito   160 VRENQNINMTCRADGFPTP-----KIIWRRE----------------DGQSITVER------KKK 197

  Fly   290 LRIANAQLL--------DTGNYTCMPTTAEAASVVVNVIND 322
            :.:.:.::|        :.|.|.|:.|.....||...:|.|
Mosquito   198 VMVYDGEVLHLTKVSRNEMGAYLCIATNGVPPSVSKRIILD 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	36/96 (38%)
		Ig	116..192	CDD:299845	27/79 (34%)
		ig	220..306	CDD:278476	15/93 (16%)
		IG_like	220..306	CDD:214653	15/93 (16%)
AgaP_AGAP004915	XP_315006.4	IG_like	51..144	CDD:214653	37/97 (38%)
		Ig	53..144	CDD:299845	36/95 (38%)
		Ig	145..225	CDD:299845	19/106 (18%)
		I-set	151..239	CDD:254352	22/115 (19%)
		IG_like	259..335	CDD:214653
		Ig	260..333	CDD:143165
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910