DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and AgaP_AGAP005069

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_313943.4	Gene:	AgaP_AGAP005069 / 1274751	VectorBaseID:	AGAP005069	Length:	354	Species:	Anopheles gambiae

Alignment Length:	238	Identity:	111/238 - (46%)
Similarity:	156/238 - (65%)	Gaps:	7/238 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 EETTYPPPVFDFGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFK 163
            ||:....|.|||.:|||||...|.|..::|||:.||||.|:||||||:||||.|..|||||:||:
Mosquito    35 EESAALQPYFDFDVPRNITVTVGQTGFLHCRVERLGDKDVAWIRKRDIHILTTGASTYTSDQRFQ 99

  Fly   164 VVRTADSKDWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGPTDLYVKVG 228
            |:....|.:|||.:||.|.||:|:||||:|||||:|:::.||||    :.:|.|.||||::||..
Mosquito   100 VLHPEGSVNWTLQIKYPQVRDTGVYECQINTEPKMSLSYTLNVI----ELRARILGPTDIFVKSD 160

  Fly   229 SSVTLTCHVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAEKLQSRLRIA 293
            |.:|:||.::|   ...::|.|:||:|..::.|..........:.:||.:|:...:.|.|||:|.
Mosquito   161 SEITMTCVIQQ---GPHELGTIFWYKGSTLIEPLAQENELLPSEKRRIIVETDWTDVLTSRLKIK 222

  Fly   294 NAQLLDTGNYTCMPTTAEAASVVVNVINDESPAAMQKSRAIRT 336
            .....|||||||:||.|::|||..:||:.:.....|.||..||
Mosquito   223 RVVQSDTGNYTCVPTMAKSASVCAHVISGKFVQTFQFSRCYRT 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	55/92 (60%)
		Ig	116..192	CDD:299845	44/75 (59%)
		ig	220..306	CDD:278476	30/85 (35%)
		IG_like	220..306	CDD:214653	30/85 (35%)
AgaP_AGAP005069	XP_313943.4	Ig	48..142	CDD:299845	55/93 (59%)
		IG_like	49..142	CDD:214653	55/92 (60%)
		I-set	152..249	CDD:254352	37/99 (37%)
		Ig	163..235	CDD:143165	24/74 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D104656at50557
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X190
TreeFam	0	0.000	Not matched by this tool.
	4	3.920