DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and AgaP_AGAP005068

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_313942.4	Gene:	AgaP_AGAP005068 / 1274750	VectorBaseID:	AGAP005068	Length:	305	Species:	Anopheles gambiae

Alignment Length:	324	Identity:	134/324 - (41%)
Similarity:	194/324 - (59%)	Gaps:	44/324 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 EETTYPPPVFDFGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFK 163
            ||:....|.|||.:|||:|...|.|..::|||:.|||:.|:|||:|||||||.|..|||||:||:
Mosquito     6 EESEALQPYFDFDVPRNLTVTVGQTGFLHCRVERLGDQDVAWIRQRDLHILTMGASTYTSDQRFQ 70

  Fly   164 VVRTADSKDWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGPTDLYVKVG 228
            |:|...|.:|||.:||.|.||||:||||:|||||:|:::.||||    :.:|.|.||:|:::|.|
Mosquito    71 VIRPEGSVNWTLQIKYPQTRDSGVYECQINTEPKMSLSYVLNVI----ELRARILGPSDIFIKSG 131

  Fly   229 SSVTLTCHVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDA-AIDLQRISMESTLAEKLQSRLRI 292
            |.:|:.|.::|   ...::|.::||:|.|...  :|..||. :.|..||::|:...:.|.|||:|
Mosquito   132 SEITMVCVIQQ---GPHELGTVFWYKGRYCQP--LAQENDIHSGDRGRITIETDWTDALTSRLKI 191

  Fly   293 ANAQLLDTGNYTCMPTTAEAASVVVNVINDESPAAMQKSRAIRTSG--SMRSSRLVLLLAMVASS 355
            ..|...|||||||:||.|.:|||..:||:.|.|||||.:.|..|.|  ::|.|..:|||..:|:
Mosquito   192 KRAIQGDTGNYTCVPTMARSASVYAHVISGEHPAAMQHNAAPSTVGHRTLRRSMCILLLLHLAT- 255

  Fly   356 VVRWLI---------GGQRIGSNSCHDSCSNLSTLHINYCNLRAKITSHLKEHRCLGPGSTVES 410
             :.:|:         ||||                     |:..:.|:..:..|...||...|:
Mosquito   256 -LLYLLSDRCCSRRSGGQR---------------------NILQRPTASHRSARGAAPGRRCET 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	55/92 (60%)
		Ig	116..192	CDD:299845	44/75 (59%)
		ig	220..306	CDD:278476	32/86 (37%)
		IG_like	220..306	CDD:214653	32/86 (37%)
AgaP_AGAP005068	XP_313942.4	IG_like	20..113	CDD:214653	55/92 (60%)
		Ig	23..99	CDD:299845	44/75 (59%)
		Ig	134..205	CDD:143165	27/75 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1457433at2759
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X190
TreeFam	0	0.000	Not matched by this tool.
	4	3.920