DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and AgaP_AGAP002494

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_312445.4	Gene:	AgaP_AGAP002494 / 1273467	VectorBaseID:	AGAP002494	Length:	283	Species:	Anopheles gambiae

Alignment Length:	254	Identity:	88/254 - (34%)
Similarity:	137/254 - (53%)	Gaps:	32/254 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 DEREAEEQPPEETTYPP-PVF-DFGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKR--DLHIL 149
            |:.|.|::..|.||:.| |.| |..|..|:||:.|....::|||::|.:::|||:|::  ::|::
Mosquito    21 DDDEQEDESAESTTHDPYPFFDDANMTANVTTQLGADVYLHCRVNDLRERTVSWVRRKGDEIHLI 85

  Fly   150 TAGILTYTSDERFKVVRTADSKDWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAK 214
            |.|..||:||.|:. ::.....||.|.::|:..||.|.||||:::.|  .:.:.:.::|..|..:
Mosquito    86 TVGRQTYSSDSRYS-LQYQPPNDWQLLIQYSNERDEGHYECQISSYP--PLVYLVYLLVVVPRVE 147

  Fly   215 AII---AGPTDLYVKVGSSVTLTC---HVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDL 273
            .|.   ....|.:.|.||::.|.|   .|.||.:.      :.|..|..:|.          .|.
Mosquito   148 IIDERGQATLDKFYKPGSTIELKCIISRVPQPTSY------VTWKHGMRMLN----------YDT 196

  Fly   274 QR--ISMESTLAE-KLQSRLRIANAQLLDTGNYTCMPTTAEAASVVVNVINDESPAAMQ 329
            .|  ||:::.|.. ...|||.||||...|||||||.......|:|.|:|:|.|:|||||
Mosquito   197 SRGGISVKTDLLPGGAMSRLYIANANRHDTGNYTCALADIAQATVSVHVLNGENPAAMQ 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	32/94 (34%)
		Ig	116..192	CDD:299845	29/77 (38%)
		ig	220..306	CDD:278476	30/91 (33%)
		IG_like	220..306	CDD:214653	30/91 (33%)
AgaP_AGAP002494	XP_312445.4	IG_like	49..129	CDD:214653	31/80 (39%)
		Ig	50..129	CDD:299845	30/79 (38%)
		IG_like	162..245	CDD:214653	33/98 (34%)
		Ig	167..>230	CDD:299845	24/78 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X190
TreeFam	0	0.000	Not matched by this tool.
	3	2.910