DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and AgaP_AGAP010742

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_311455.4	Gene:	AgaP_AGAP010742 / 1272555	VectorBaseID:	AGAP010742	Length:	1195	Species:	Anopheles gambiae

Alignment Length:	218	Identity:	51/218 - (23%)
Similarity:	84/218 - (38%)	Gaps:	60/218 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 MPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSD-------------ERFK 163
            :||::....|..|.:.|.:.||                 .|.:.:|.|             .|:.
Mosquito    13 VPRDLQVLEGTEALLRCEIYNL-----------------VGAVQWTKDGFALGFSHTIPGYPRYS 60

  Fly   164 VVRTADSKDWTLHVKYAQPRDSGIYECQVNTEPKISMAFRLN---VIVTPPDAKAIIAGPTDLYV 225
            |:...:...:.|.:..|...|...|:|||. ..|.:.|.|.|   .:::||.:..|.....:..|
Mosquito    61 VLADRNLGIYNLRISNASIEDDAEYQCQVG-PAKFNSAIRANARLTVISPPSSIEIQGHSRNAKV 124

  Fly   226 KV--GSSVTLTCHVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAE---- 284
            :|  |..:||||.|    ::|:.:..|.||||.      ..:.:|        ::|:.:.|
Mosquito   125 EVREGQDLTLTCVV----SNAKPVAQIVWYRGK------TEYKSD--------TIENKVTETEGK 171

  Fly   285 --KLQSRLRIANAQLLDTGNYTC 305
              .:.|:|||......|...|||
Mosquito   172 RYTVSSQLRIKPTSDDDYMEYTC 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	23/108 (21%)
		Ig	116..192	CDD:299845	15/88 (17%)
		ig	220..306	CDD:278476	25/94 (27%)
		IG_like	220..306	CDD:214653	25/94 (27%)
AgaP_AGAP010742	XP_311455.4	Ig	12..106	CDD:299845	23/110 (21%)
		IG_like	14..106	CDD:214653	23/109 (21%)
		IG_like	124..197	CDD:214653	25/89 (28%)
		Ig	133..215	CDD:299845	22/80 (28%)
		Ig	221..297	CDD:299845
		I-set	419..509	CDD:254352
		Ig	438..509	CDD:299845
		Ig	530..599	CDD:299845
		IG_like	531..610	CDD:214653
		IG_like	623..704	CDD:214653
		IGc2	628..694	CDD:197706
		IG_like	714..798	CDD:214653
		Ig	725..786	CDD:299845
		Ig	798..905	CDD:299845
		I-set	802..900	CDD:254352
		FN3	904..991	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910