DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr2 and AgaP_AGAP000659

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_311185.5	Gene:	AgaP_AGAP000659 / 1272415	VectorBaseID:	AGAP000659	Length:	2177	Species:	Anopheles gambiae

Alignment Length:	245	Identity:	65/245 - (26%)
Similarity:	94/245 - (38%)	Gaps:	54/245 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 ETTYP----PPVFDFGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDE 160
            :|:.|    |||       |.|...|..|.:|||.......|:.||......|.|:        .
Mosquito   383 KTSIPFMEIPPV-------NQTILDGKDATMNCRAIAAPTPSIQWIFNDTYPIETS--------S 432

  Fly   161 RFKVVRTADSKDWTLHVKYAQPRDSGIYEC-QVNTEPKISMAFRLNVIVTPPDAKAIIAGPTDLY 224
            |.:::.:.|     |.:...:..|.|:|.| :.|...::..:..|.|:|    ...|...|.|..
Mosquito   433 RMQILDSGD-----LLISNVRETDGGLYTCIRENEAGRVIGSGYLTVLV----RTQINRPPADTT 488

  Fly   225 VKVGSSVTLTCHVKQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAI-DLQRISMESTLAEKLQS 288
            |.:|.|..|.|.|....|...:|.   |||          .||...| :.|||.:      |...
Mosquito   489 VLLGHSAALECGVSSDPTVPYNID---WYR----------EPNRLPIKNSQRIGV------KKDG 534

  Fly   289 RLRIANAQLLDTGNYTCMPTTA---EAASVVVNVINDESPAAMQKSRAIR 335
            .|.|...:..|.|.|:|:.|:.   |..|..::||  |.|.|....:|:|
Mosquito   535 TLEITEVRPSDVGQYSCIVTSPGGNETRSARLSVI--ELPFAPSNVQAVR 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	21/93 (23%)
		Ig	116..192	CDD:299845	18/76 (24%)
		ig	220..306	CDD:278476	25/86 (29%)
		IG_like	220..306	CDD:214653	25/86 (29%)
AgaP_AGAP000659	XP_311185.5	I-set	6..84	CDD:254352
		IGc2	21..79	CDD:197706
		I-set	195..290	CDD:254352
		IGc2	211..273	CDD:197706
		Ig	293..382	CDD:299845
		I-set	294..382	CDD:254352
		IG_like	393..474	CDD:214653	23/100 (23%)
		IGc2	401..464	CDD:197706	18/75 (24%)
		Ig	484..568	CDD:299845	29/102 (28%)
		IG_like	484..568	CDD:214653	29/102 (28%)
		FN3	575..675	CDD:238020	2/8 (25%)
		FN3	684..779	CDD:238020
		FN3	787..909	CDD:238020
		FN3	914..998	CDD:238020
		FN3	1012..1101	CDD:238020
		FN3	1114..1228	CDD:238020
		FN3	1237..1330	CDD:238020
		FN3	1335..1427	CDD:238020
		FN3	1433..1528	CDD:238020
		fn3	1538..1628	CDD:278470
		FN3	1642..1743	CDD:238020
		FN3	1748..1839	CDD:238020
		FN3	1846..1935	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910