DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr2 and si:dkey-24p1.7

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_005173465.1	Gene:	si:dkey-24p1.7 / 101883966	ZFINID:	ZDB-GENE-121214-215	Length:	598	Species:	Danio rerio

Alignment Length:	351	Identity:	63/351 - (17%)
Similarity:	108/351 - (30%)	Gaps:	144/351 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FGCIATPILV-----------IMISISRAWTMQQQH-------LSPAIQQHPA-----VKSLSHL 49
            |.|..||.::           |.:..::...:..:|       |.|...||..     |:..:..
Zfish   165 FPCPETPPVITWWIKTKEENYIKLDNNKITQVHSEHVYYSYLTLIPTSDQHDGTVGCDVRYGNKK 229

  Fly    50 VDGNDNL-------LPMVSAPSSIDNDYVYIASVNRKFPQFGNSIDDEREAEEQPPEETTYPPPV 107
            ::.|:.|       |.:|...:.::.|.:.:....|..|...|                    ||
Zfish   230 INTNNTLEVKYVQALQIVGENTLMEGDTLNLTCTFRSHPPASN--------------------PV 274

  Fly   108 FDFGMPRNITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERFKVVRTADSKD 172
            :.|                |...|||..::            :||
Zfish   275 WRF----------------NGNTDNLNTQT------------SAG-------------------- 291

  Fly   173 WTLHVKYAQPRDSGIYECQVNTEPKISMAFRLNVIVTPPDAKAIIAGPTDLYVKVGSSVTLTCHV 237
             ||.:.......:|||.|::....|     .||..:|....:..|.|...|  |.|.::.|||..
Zfish   292 -TLMIANVGKEHAGIYVCEMTYMNK-----TLNASITINITEVNILGENRL--KKGDTLNLTCSF 348

  Fly   238 KQPATSAQDIGPIYWYRGPYILTPFVAHPNDAAIDLQRISMESTLAEKLQSRLRIANAQLLD--- 299
            |....|:.:  |::.:.|.                          |:||:::...||. ::|
Zfish   349 KNHPQSSSN--PVWSFNGD--------------------------ADKLKNQASAANL-IIDNVT 384

  Fly   300 ---TGNYTCMPTTAEA---ASVVVNV 319
               .|.|.|..|..:.   ||:.|::
Zfish   385 KEHAGIYACEMTYMKKTLNASITVDI 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	14/92 (15%)
		Ig	116..192	CDD:299845	12/75 (16%)
		ig	220..306	CDD:278476	18/91 (20%)
		IG_like	220..306	CDD:214653	18/91 (20%)
si:dkey-24p1.7	XP_005173465.1	Ig	27..132	CDD:299845
		IG_like	251..325	CDD:214653	23/147 (16%)
		Ig	254..323	CDD:299845	22/142 (15%)
		ig	336..394	CDD:278476	18/88 (20%)
		IG_like	339..408	CDD:214653	20/97 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000