DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and LOC100496188

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_031748713.1	Gene:	LOC100496188 / 100496188	-ID:	-	Length:	852	Species:	Xenopus tropicalis

Alignment Length:	334	Identity:	71/334 - (21%)
Similarity:	110/334 - (32%)	Gaps:	115/334 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 ETTYPPPVFDFGMPRNITTRTGHTAAINC--RVDN--LGDK--SVSWIRKRDLHILTAGILTYTS 158
            |.|.||   |...|      .|..|.:.|  ||||  :..|  ::.|      |.....:|.|
Frog    28 EVTVPP---DQSSP------MGRDALLPCTFRVDNPPMNPKFLAILW------HFGDKEVLRY-- 75

  Fly   159 DERFKVVRTADSKD--------WTLHVKYAQPRDSGIYECQVNTEPKI-SMAFRLNVIVTPPDAK 214
            |.:.||.....|.|        .:|.:......|.|.|.|.|...|:. ....||.:...|   :
Frog    76 DNKGKVSSPRVSIDERALLEGNASLSLSNVTVSDGGTYRCSVIYSPETQKKEIRLRIHALP---E 137

  Fly   215 AIIAGPTDLYVKVGSSVTLTCHVKQPATSAQDIGP----IYWYRGPYILTPFVAHPNDAAIDLQR 275
            .::|..| |....|::  |.|       |..|..|    :.|.|...:|      ||.|...||:
Frog   138 VVVAKRT-LVRNQGTA--LRC-------SVTDFYPQRITVTWLRNGKVL------PNSALGPLQQ 186

  Fly   276 ISMESTLAEKLQSRLRIANAQLLDTGNYTCM--------------------PTTAEAASVVVN-- 318
             :.:.|.  :|.|.|.:..:...||....|:                    |.:.:..|..:|
Frog   187 -NADGTF--RLNSTLTLTPSDTEDTPEIACLVQHESLPTPRRDSFRVQYGVPPSVQVYSAKINGR 248

  Fly   319 ---------------------VINDESPAAMQKSRAIRTSGSMRSSRLVLLLAMVASSVVRWLIG 362
                                 ::|.:.|..::|||    .|..::....::..          .|
Frog   249 PEQVLVCEASQFQPEPVRIQWLLNGKIPEDLKKSR----DGGFKTGSYYVINP----------TG 299

  Fly   363 GQRIGSNSC 371
            |.::|:.||
Frog   300 GIQVGNISC 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	27/107 (25%)
		Ig	116..192	CDD:299845	22/89 (25%)
		ig	220..306	CDD:278476	22/89 (25%)
		IG_like	220..306	CDD:214653	22/89 (25%)
LOC100496188	XP_031748713.1	V-set	30..133	CDD:400157	31/119 (26%)
		Ig strand B	41..48	CDD:409353	1/6 (17%)
		CDR1	49..58	CDD:409353	4/8 (50%)
		FR2	60..70	CDD:409353	2/15 (13%)
		Ig strand C	60..67	CDD:409353	1/12 (8%)
		Ig strand C'	76..79	CDD:409353	1/2 (50%)
		FR3	82..117	CDD:409353	7/34 (21%)
		Ig strand D	85..91	CDD:409353	2/5 (40%)
		Ig strand E	97..103	CDD:409353	1/5 (20%)
		Ig strand A	136..143	CDD:409353	2/9 (22%)
		Ig strand B	150..160	CDD:409353	4/18 (22%)
		C1-set	153..220	CDD:400140	20/82 (24%)
		Ig strand C	165..171	CDD:409353	1/5 (20%)
		Ig strand C'	173..176	CDD:409353	0/2 (0%)
		Ig strand D	180..187	CDD:409353	3/7 (43%)
		Ig strand E	190..200	CDD:409353	4/11 (36%)
		Ig strand F	210..217	CDD:409353	1/6 (17%)
		Ig	234..315	CDD:416386	14/89 (16%)
		Ig strand A	235..242	CDD:409353	1/6 (17%)
		Ig strand B	251..258	CDD:409353	0/6 (0%)
		Ig strand C	264..270	CDD:409353	0/5 (0%)
		Ig strand C'	273..275	CDD:409353	0/1 (0%)
		Ig strand E	287..295	CDD:409353	0/7 (0%)
		Ig strand F	302..312	CDD:409353	3/7 (43%)
		IgC1	<617..702	CDD:409354
		Ig strand C	628..632	CDD:409354
		Ig strand E	669..673	CDD:409354
		Ig strand F	684..689	CDD:409354
		Ig strand G	699..702	CDD:409354
		Ig	701..804	CDD:416386
		Ig strand B	712..729	CDD:409353
		Ig strand C	734..741	CDD:409353
		Ig strand C'	750..753	CDD:409353
		Ig strand E	766..781	CDD:409353
		Ig strand F	789..795	CDD:409353
		Ig strand G	798..804	CDD:409353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910