DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr2 and ntm

DIOPT Version :9

Sequence 1:	NP_001014480.4	Gene:	dpr2 / 3346227	FlyBaseID:	FBgn0261871	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	356	Identity:	82/356 - (23%)
Similarity:	136/356 - (38%)	Gaps:	130/356 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 DFGMPR---NITTRTGHTAAINCRVDNLGDKSVSWIRKRDLHILTAGILTYTSDERF----KVVR 166
            |.|.|:   |:|.|.|.:|.:.|.|||...: |:|:.:        ..:.||.::::    :||.
Frog    36 DAGFPKAMDNVTVRQGDSAILRCTVDNRVTR-VAWLNR--------STILYTGNDKWSIDPRVVL 91

  Fly   167 TADSK-DWTLHVKYAQPRDSGIYECQVNTE--PKISMAFRLNVIV-TPPDAKAIIAGPTDLYVKV 227
            .|::| .:::.::.....|.|.|.|.|.|:  ||.|   |:::|| .||   .|:...:.:.|..
Frog    92 LANTKSQYSIEIQNVDIYDEGPYTCSVQTDNHPKTS---RVHLIVQVPP---RIVDISSSIAVNE 150

  Fly   228 GSSVTLTC------------------------------------------------HVKQP---- 240
            ||:|:|.|                                                .|..|
Frog   151 GSNVSLICIANGRPEPVVNWRYLSPKARGFVSEDEYLEITGITREQSGIYECSASNDVSAPDVRR 215

  Fly   241 ----------ATSAQDIGPIYWYRGPYIL---------TPFVAHPNDAAIDLQRISMESTLAEKL 286
                      ...||:||....:||  ||         ..|..:..|     :|:| :|....|:
Frog   216 VKLTVNYPPYILDAQNIGAPLGHRG--ILQCEASAVPAADFFWYKED-----KRLS-DSWRGVKV 272

  Fly   287 QSRLRIANAQLL-----DTGNYTCMPTTA---EAASVVVNVI--NDESPAAMQKSRAIRT----- 336
            ::|..|:....|     |.||||||....   ..||:::..:  :..||...::|.|..|
Frog   273 ENRETISRVTFLNVSEQDYGNYTCMAKNLLGHSNASIILFELFQSTSSPLLQEESTAALTPLKGP 337

  Fly   337 -------SGSMRSS---RLVLLLAMVASSVV 357
                   |||.:.|   .|::||.::..|::
Frog   338 GAVHDGNSGSTQCSFCAPLLILLLLLPFSLL 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr2	NP_001014480.4	IG_like	113..206	CDD:214653	28/102 (27%)
		Ig	116..192	CDD:299845	20/80 (25%)
		ig	220..306	CDD:278476	30/161 (19%)
		IG_like	220..306	CDD:214653	30/161 (19%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	27/99 (27%)
		IG_like	45..133	CDD:214653	27/99 (27%)
		IG_like	143..220	CDD:214653	8/76 (11%)
		IGc2	150..209	CDD:197706	5/58 (9%)
		ig	227..311	CDD:278476	26/91 (29%)
		IG_like	230..311	CDD:214653	25/88 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000